|
|
|
Sample: |
Liver Receptor Homolog-1 monomer, 64 kDa Homo sapiens protein
Peroxisome Proliferator-Activated Receptor Gamma Coactivator-1 Alpha monomer, 2 kDa Homo sapiens protein
CYP7A1 Promoter Forward monomer, 4 kDa Homo sapiens DNA
CYP7A1 Promoter Reverse monomer, 4 kDa Homo sapiens DNA
|
Buffer: |
20 mM TRIS, 150 mM NaCl, 2% v/v glycerol, 0.5 mM CHAPS, 5 mM DTT, pH: 7.5
|
Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 26
|
Integrated Structural Modeling of Full-Length LRH-1 Reveals Inter-domain Interactions Contribute to Receptor Structure and Function.
Structure (2020)
Seacrist CD, Kuenze G, Hoffmann RM, Moeller BE, Burke JE, Meiler J, Blind RD
|
RgGuinier |
3.8 |
nm |
Dmax |
13.0 |
nm |
VolumePorod |
76 |
nm3 |
|
|
|
|
|
Sample: |
Tegument protein UL7 monomer, 34 kDa Human alphaherpesvirus 1 … protein
Tegument protein UL51 dimer, 30 kDa Human alphaherpesvirus 1 … protein
|
Buffer: |
20 mM tris, 200 mM NaCl, 3% (v/v) glycerol, 0.25 mM TCEP, pH: 7.5
|
Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2019 May 16
|
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.
Elife 9 (2020)
Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC
|
RgGuinier |
3.0 |
nm |
Dmax |
11.5 |
nm |
VolumePorod |
116 |
nm3 |
|
|
|
|
|
Sample: |
Tegument protein UL7 dimer, 68 kDa Human alphaherpesvirus 1 … protein
Tegument protein UL51 tetramer, 102 kDa Human alphaherpesvirus 1 … protein
|
Buffer: |
20 mM HEPES, 200 mM NaCl, 3% (v/v) glycerol, 1 mM DTT, pH: 7.5
|
Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2019 May 16
|
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.
Elife 9 (2020)
Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC
|
RgGuinier |
4.6 |
nm |
Dmax |
19.7 |
nm |
VolumePorod |
340 |
nm3 |
|
|
|
|
|
Sample: |
Tegument protein UL7 monomer, 34 kDa Human alphaherpesvirus 1 … protein
Tegument protein UL51 dimer, 51 kDa Human alphaherpesvirus 1 protein
|
Buffer: |
20 mM HEPES, 200 mM NaCl, 3% (v/v) glycerol, 1 mM DTT, pH: 7.5
|
Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2019 May 16
|
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex.
Elife 9 (2020)
Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC
|
RgGuinier |
4.0 |
nm |
Dmax |
18.2 |
nm |
VolumePorod |
160 |
nm3 |
|
|
|
|
|
Sample: |
Cytoplasmic envelopment protein 3 monomer, 12 kDa Human alphaherpesvirus 1 protein
|
Buffer: |
50 mM HEPES, 100 mM NaCl, 0.5 mM tris(2-carboxyethyl)phosphine (TCEP),, pH: 7.5
|
Experiment: |
SAXS
data collected at G1, Cornell High Energy Synchrotron Source (CHESS) on 2017 Jun 4
|
Conserved Outer Tegument Component UL11 from Herpes Simplex Virus 1 Is an Intrinsically Disordered, RNA-Binding Protein.
mBio 11(3) (2020)
Metrick CM, Koenigsberg AL, Heldwein EE
|
RgGuinier |
2.4 |
nm |
Dmax |
12.0 |
nm |
VolumePorod |
30 |
nm3 |
|
|
|
|
|
Sample: |
Tumor necrosis factor receptor superfamily member 5 monomer, 19 kDa Homo sapiens protein
Human 341G2 F(ab) monomer, 73 kDa Homo sapiens protein
|
Buffer: |
Phosphate-buffered saline, pH: 7
|
Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2019 Sep 18
|
Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity
Cancer Cell (2020)
Yu X, Chan H, Fisher H, Penfold C, Kim J, Inzhelevskaya T, Mockridge C, French R, Duriez P, Douglas L, English V, Verbeek J, White A, Tews I, Glennie M, Cragg M
|
RgGuinier |
3.7 |
nm |
Dmax |
13.4 |
nm |
VolumePorod |
97 |
nm3 |
|
|
|
|
|
Sample: |
E3 ubiquitin-protein ligase UHRF1 monomer, 21 kDa Homo sapiens protein
|
Buffer: |
SAXS Buffer, pH: 7.5
|
Experiment: |
SAXS
data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2018 Nov 26
|
Serine 298 Phosphorylation in Linker 2 of UHRF1 Regulates Ligand-Binding Property of its Tandem Tudor Domain
Journal of Molecular Biology (2020)
Kori S, Jimenji T, Ekimoto T, Sato M, Kusano F, Oda T, Unoki M, Ikeguchi M, Arita K
|
RgGuinier |
2.0 |
nm |
Dmax |
6.6 |
nm |
VolumePorod |
26 |
nm3 |
|
|
|
|
|
Sample: |
E3 ubiquitin-protein ligase UHRF1 monomer, 21 kDa Homo sapiens protein
|
Buffer: |
SAXS buffer, pH: 7.5
|
Experiment: |
SAXS
data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2018 Nov 26
|
Serine 298 Phosphorylation in Linker 2 of UHRF1 Regulates Ligand-Binding Property of its Tandem Tudor Domain
Journal of Molecular Biology (2020)
Kori S, Jimenji T, Ekimoto T, Sato M, Kusano F, Oda T, Unoki M, Ikeguchi M, Arita K
|
RgGuinier |
2.1 |
nm |
Dmax |
7.0 |
nm |
VolumePorod |
29 |
nm3 |
|
|
|
|
|
Sample: |
BRME1 dimer, 23 kDa Mus musculus protein
Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
|
Buffer: |
20 mM Tris pH 8.0, 150 mM KCl, pH: 8
|
Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2019 Oct 7
|
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
|
RgGuinier |
5.0 |
nm |
Dmax |
19.0 |
nm |
VolumePorod |
104 |
nm3 |
|
|
|
|
|
Sample: |
Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
|
Buffer: |
20 mM Tris pH 8.0, 150 mM KCl, pH: 8
|
Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2019 Oct 7
|
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells
Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
|
RgGuinier |
4.6 |
nm |
Dmax |
16.0 |
nm |
VolumePorod |
88 |
nm3 |
|
|