Small Angle Scattering Biological Data Bank SASBDB


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6 hits found for Lalic

SASDWX3 – Full length peroxisome proliferator-activated receptor gamma (PPARγ)

Peroxisome proliferator-activated receptor gamma experimental SAS data

Peroxisome proliferator-activated receptor gamma Kratky plot

Sample:	Peroxisome proliferator-activated receptor gamma monomer, 58 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 150 mM KCl, 1 mM TCEP, 2% v/v glycerol, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2021 Dec 12

Autoinhibition of untimely DNA binding by structural disorder in the full-length peroxisome proliferator-activated receptors (PPARs) Nature Communications (2026)
Lalic M, Thomsen E, Thomasen F, Udupa A, Salehian Andersen E, Kuppermann S, Christensen C, Holm-Olesen E, Saar D, Prestel A, Bauer L, McKenna J, Olsen J, Mandrup S, Hartmann-Petersen R, Jeffries C, St...

R_g^Guinier	3.7	nm
D_max	16.5	nm
Volume^Porod	123	nm³

SASDWY3 – N-terminal truncation of peroxisome proliferator-activated receptor gamma (ΔAB-PPARγ)

Sample:	Peroxisome proliferator-activated receptor gamma monomer, 43 kDa Homo sapiens protein
Buffer:	25 mM HEPES, 150 mM NaCl, 5 mM NaNO3, 5 mM TCEP, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2022 Mar 20

R_g^Guinier	2.4	nm
D_max	8.4	nm
Volume^Porod	71	nm³

SASDWZ3 – The intrinsically disordered N-terminal AB domain of peroxisome proliferator-activated receptor gamma (PPARγ-AB)

Sample:	Peroxisome proliferator-activated receptor gamma monomer, 15 kDa Homo sapiens protein
Buffer:	25 mM HEPES, 150 mM NaCl, 5 mM NaNO3, 5 mM TCEP, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2023 Mar 16

R_g^Guinier	3.5	nm
D_max	16.0	nm
Volume^Porod	21	nm³

SASDW24 – The N-terminal AB domain and DNA binding domain of peroxisome proliferator-activated receptor alpha (PPARα-ABDBD)

Peroxisome proliferator-activated receptor alpha experimental SAS data

Peroxisome proliferator-activated receptor alpha Kratky plot

Sample:	Peroxisome proliferator-activated receptor alpha monomer, 20 kDa Homo sapiens protein
Buffer:	25 mM HEPES, 150 mM NaCl, 5 mM NaNO3, 5 mM TCEP, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2023 Mar 16

R_g^Guinier	2.4	nm
D_max	10.3	nm
Volume^Porod	37	nm³

SASDW34 – The intrinsically disordered N-terminal AB domain of peroxisome proliferator-activated receptor alpha (PPARα-AB)

Sample:	Peroxisome proliferator-activated receptor alpha monomer, 10 kDa Homo sapiens protein
Buffer:	25 mM HEPES, 150 mM NaCl, 5 mM NaNO3, 5 mM TCEP, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2023 Mar 16

R_g^Guinier	3.0	nm
D_max	11.0	nm
Volume^Porod	16	nm³

SASDXC6 – Sodium/hydrogen exchanger 6 protein (HsNHE6) C-terminal end (G586-A701)

Sodium/hydrogen exchanger 6 experimental SAS data

Sample:	Sodium/hydrogen exchanger 6 monomer, 13 kDa Homo sapiens protein
Buffer:	20 mM HEPES, 150 mM NaCl, 5 mM DTT, pH: 7.4
Experiment:	SAXS data collected at EMBL P12, PETRA III on 2024 Dec 14

Integrative structural analysis of human endosomal NHE6 reveals a lipid-associated gate and disordered C-terminus Nature Communications (2026)
...Lalic M, Havelund J, Jeria Cerda C, Ginsthofer M, Ostendorf J, Ma L, Morrow E, Færgeman N, Pedersen S, Kragelund B, Autzen H

R_g^Guinier