SASBDB entries for UniProt ID:

SASDJK8 – N-terminal Angiopoietin-like protein 3 Hexamer

UniProt ID: Q9Y5C1 (16-224) Angiopoietin-like protein 3 (N-terminal)
Angiopoietin-like protein 3 (N-terminal) experimental SAS data
DAMMIN model
Sample: Angiopoietin-like protein 3 (N-terminal) hexamer, 161 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 5.6 nm
Dmax 34.0 nm
VolumePorod 380 nm3

SASDJL8 – N-terminal Angiopoietin-like protein 3 Trimer

UniProt ID: Q9Y5C1 (16-224) Angiopoietin-related protein 3
Angiopoietin-related protein 3 experimental SAS data
DAMMIN model
Sample: Angiopoietin-related protein 3 trimer, 81 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl pH 7.5, 400 mM NaCl, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 12
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 4.6 nm
Dmax 21.5 nm
VolumePorod 71 nm3

SASDJM8 – N-terminal Angiopoietin-like protein 4 Trimer

UniProt ID: Q9BY76 (26-161) Angiopoietin-related protein 4
Angiopoietin-related protein 4 experimental SAS data
DAMMIN model
Sample: Angiopoietin-related protein 4 trimer, 46 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl pH 7.4, 300 mM NaCl, 100 mM betaine, 500 mM arginine, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2017 Nov 8
Comparison of angiopoietin-like protein 3 and 4 reveals structural and mechanistic similarities. J Biol Chem :100312 (2021)
Gunn KH, Gutgsell AR, Xu Y, Johnson CV, Liu J, Neher SB
RgGuinier 4.7 nm
Dmax 16.0 nm
VolumePorod 69 nm3

SASDJR8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358

UniProt ID: Q8TB36 (1-294) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 dimer, 68 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 21
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.1 nm
Dmax 101.6 nm
VolumePorod 111 nm3

SASDJS8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 with hexadecanedioic acid

UniProt ID: Q8TB36 (1-294) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 dimer, 68 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.1 nm
Dmax 9.2 nm
VolumePorod 112 nm3

SASDJT8 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358

UniProt ID: Q8TB36 (1-294) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 monomer, 34 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 21
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.7 nm
Dmax 92.3 nm
VolumePorod 71 nm3

SASDJU8 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 with hexadecanedioic acid

UniProt ID: Q8TB36 (1-294) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆295-358 monomer, 34 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.5 nm
Dmax 8.9 nm
VolumePorod 63 nm3

SASDJV8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358

UniProt ID: Q8TB36 (1-302) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358 experimental SAS data
CORAL model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358 dimer, 70 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2020 Jun 28
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.1 nm
Dmax 9.9 nm
VolumePorod 106 nm3

SASDJW8 – Monomeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A

UniProt ID: Q8TB36 (1-302) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆303-358, mutant Y29E/C88A monomer, 35 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2020 Jun 28
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 2.5 nm
Dmax 8.7 nm
VolumePorod 59 nm3

SASDJX8 – Dimeric human ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358

UniProt ID: Q8TB36 (1-318) Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358
Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 experimental SAS data
GASBOR model
Sample: Ganglioside-induced differentiation-associated protein 1, construct GDAP1∆319-358 dimer, 74 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2019 Jul 11
Structure of the Complete Dimeric Human GDAP1 Core Domain Provides Insights into Ligand Binding and Clustering of Disease Mutations Frontiers in Molecular Biosciences 7 (2021)
Nguyen G, Sutinen A, Raasakka A, Muruganandam G, Loris R, Kursula P
RgGuinier 3.5 nm
Dmax 10.8 nm
VolumePorod 130 nm3