SASBDB entries for UniProt ID:

SASDLP9 – Hepatocyte growth factor HGF/SF receptor - fragment MET567 in complex with the minimal hepatocyte growth factor mimic K1K1

UniProt ID: None (None-None) minimal hepatocyte growth factor mimic K1K1

UniProt ID: P08581 (25-567) Hepatocyte growth factor receptor
minimal hepatocyte growth factor mimic K1K1Hepatocyte growth factor receptor experimental SAS data
CORAL model
Sample: Minimal hepatocyte growth factor mimic K1K1 monomer, 19 kDa synthetic construct protein
Hepatocyte growth factor receptor monomer, 62 kDa Homo sapiens protein
Buffer: 25 mM Tris, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2018 Jan 23
Dimerization of kringle 1 domain from hepatocyte growth factor/scatter factor provides a potent MET receptor agonist Life Science Alliance 5(12):e202201424 (2022)
de Nola G, Leclercq B, Mougel A, Taront S, Simonneau C, Forneris F, Adriaenssens E, Drobecq H, Iamele L, Dubuquoy L, Melnyk O, Gherardi E, de Jonge H, Vicogne J
RgGuinier 3.7 nm
Dmax 14.3 nm
VolumePorod 136 nm3

SASDLQ9 – Von Willebrand Factor C6 domain wildtype

UniProt ID: P04275 (2647-2720) von Willebrand factor C6 domain wild type
von Willebrand factor C6 domain wild type experimental SAS data
von Willebrand factor C6 domain wild type Kratky plot
Sample: Von Willebrand factor C6 domain wild type monomer, 9 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2016 Dec 11
Structure and dynamics of the von Willebrand Factor C6 domain Journal of Structural Biology 214(4):107923 (2022)
Chen P, Kutzki F, Mojzisch A, Simon B, Xu E, Aponte-Santamaría C, Horny K, Jeffries C, Schneppenheim R, Wilmanns M, Brehm M, Gräter F, Hennig J
RgGuinier 1.7 nm
Dmax 6.6 nm
VolumePorod 12 nm3

SASDLR9 – von Willebrand factor C6 domain G2705K mutant

UniProt ID: P04275 (2647-2720) von Willebrand factor C6 domain G2705K mutant
von Willebrand factor C6 domain G2705K mutant experimental SAS data
von Willebrand factor C6 domain G2705K mutant Kratky plot
Sample: Von Willebrand factor C6 domain G2705K mutant monomer, 9 kDa Homo sapiens protein
Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 2
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 1.8 nm
Dmax 6.7 nm
VolumePorod 11 nm3

SASDLS9 – von Willebrand factor C6-CK wildtype

UniProt ID: P04275 (2647-2813) von Willebrand factor C6-CK wildtype
von Willebrand factor C6-CK wildtype experimental SAS data
von Willebrand factor C6-CK wildtype Kratky plot
Sample: Von Willebrand factor C6-CK wildtype dimer, 41 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Aug 18
Structure and dynamics of the von Willebrand Factor C6 domain
RgGuinier 3.3 nm
Dmax 15.0 nm
VolumePorod 90 nm3

SASDLT9 – von Willebrand factor C6-CK G2705R

UniProt ID: P04275 (2647-2813) von Willebrand factor C6-CK G2705R
von Willebrand factor C6-CK G2705R experimental SAS data
von Willebrand factor C6-CK G2705R Kratky plot
Sample: Von Willebrand factor C6-CK G2705R dimer, 42 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Aug 18
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 3.5 nm
Dmax 16.5 nm
VolumePorod 95 nm3

SASDLU9 – von Willebrand factor C6-CK G2705K

UniProt ID: P04275 (2647-2813) von Willebrand factor C6-CK G2705K
von Willebrand factor C6-CK G2705K experimental SAS data
von Willebrand factor C6-CK G2705K Kratky plot
Sample: Von Willebrand factor C6-CK G2705K dimer, 41 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Aug 18
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 3.5 nm
Dmax 16.0 nm
VolumePorod 106 nm3

SASDLV9 – von Willebrand factor D4N-CK wildtype

UniProt ID: P04275 (1873-2813) von Willebrand factor D4N-CK wildtype
von Willebrand factor D4N-CK wildtype experimental SAS data
von Willebrand factor D4N-CK wildtype Kratky plot
Sample: Von Willebrand factor D4N-CK wildtype dimer, 211 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Jun 23
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 7.8 nm
Dmax 34.8 nm
VolumePorod 637 nm3

SASDLW9 – von Willebrand factor D4N-CK G2705R

UniProt ID: P04275 (1873-2813) von Willebrand factor D4N-CK G2705R
von Willebrand factor D4N-CK G2705R experimental SAS data
von Willebrand factor D4N-CK G2705R Kratky plot
Sample: Von Willebrand factor D4N-CK G2705R dimer, 211 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Jun 23
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 11.4 nm
Dmax 68.5 nm
VolumePorod 1800 nm3

SASDLX9 – von Willebrand factor D4N-CK G2705K

UniProt ID: P04275 (1873-2813) von Willebrand factor D4N-CK G2705K
von Willebrand factor D4N-CK G2705K experimental SAS data
von Willebrand factor D4N-CK G2705K Kratky plot
Sample: Von Willebrand factor D4N-CK G2705K dimer, 211 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Jun 23
Structure and dynamics of the von Willebrand Factor C6 domain
Emma-Ruoqi Xu
RgGuinier 9.8 nm
Dmax 52.0 nm
VolumePorod 917 nm3

SASDLY9 – Mouse guanylate-binding protein 7 - mGBP7

UniProt ID: Q91Z40 (2-638) Gbp6 protein (Gbp7 - Gbp6 protein Mus musculus)
Gbp6 protein (Gbp7 - Gbp6 protein Mus musculus) experimental SAS data
GASBOR model
Sample: Gbp6 protein (Gbp7 - Gbp6 protein Mus musculus) dimer, 148 kDa Mus musculus protein
Buffer: 50 mM Tris, 5 mM MgCl, 2 mM DTT, pH: 8
Experiment: SAXS data collected at Xenocs Xeuss 2.0 Q-Xoom, Center for Structural Studies, Heinrich-Heine-University on 2019 Oct 2
Integrative modeling of guanylate binding protein dimers Protein Science (2023)
Schumann W, Loschwitz J, Reiners J, Degrandi D, Legewie L, Stühler K, Pfeffer K, Poschmann G, Smits S, Strodel B
RgGuinier 5.4 nm
Dmax 17.0 nm
VolumePorod 176 nm3