SASBDB entries for UniProt ID:

SASDVK6 – Dipeptidyl peptidase 8 (DPP8) with compound 42

UniProt ID: Q6V1X1-1 (None-None) Isoform 1 of Dipeptidyl peptidase 8
Isoform 1 of Dipeptidyl peptidase 8 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 8 dimer, 208 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2023 Oct 14
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.2 nm
Dmax 13.7 nm
VolumePorod 277 nm3

SASDVL6 – apo Dipeptidyl peptidase 9 (DPP9 apo)

UniProt ID: Q86TI2-1 (1-863) Isoform 1 of Dipeptidyl peptidase 9
Isoform 1 of Dipeptidyl peptidase 9 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 9 dimer, 198 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2023 Sep 23
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.2 nm
Dmax 13.3 nm
VolumePorod 290 nm3

SASDVM6 – Dipeptidyl peptidase 9 (DPP9) with compound 42

UniProt ID: Q86TI2-1 (1-863) Isoform 1 of Dipeptidyl peptidase 9
Isoform 1 of Dipeptidyl peptidase 9 experimental SAS data
BILBOMD model
Sample: Isoform 1 of Dipeptidyl peptidase 9 dimer, 198 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2023 Sep 23
Computational study of DPP8 and DPP9: fundamental insights and inhibitor design University of Antwerp PhD thesis c:irua:209673 (2024)
Olivier Beyens, Yann Sterckx
RgGuinier 4.1 nm
Dmax 12.5 nm
VolumePorod 274 nm3

SASDVQ6 – Retriever complex

UniProt ID: Q7Z3J2 (1-963) VPS35 endosomal protein-sorting factor-like

UniProt ID: Q9UBQ0 (1-182) Vacuolar protein sorting-associated protein 29

UniProt ID: O14972 (1-297) Vacuolar protein sorting-associated protein 26C
VPS35 endosomal protein-sorting factor-likeVacuolar protein sorting-associated protein 29Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: VPS35 endosomal protein-sorting factor-like monomer, 110 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 29 monomer, 21 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 28
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 5.2 nm
Dmax 21.5 nm
VolumePorod 256 nm3

SASDVR6 – Vacuolar protein sorting-associated protein 26C (VPS26C)

UniProt ID: O14972 (1-297) Vacuolar protein sorting-associated protein 26C
Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Apr 22
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 2.7 nm
Dmax 9.4 nm
VolumePorod 44 nm3

SASDVV6 – Extended single alpha-helix (SAH) region of Drebrin

UniProt ID: Q16643 (173-238) Drebrin
Drebrin experimental SAS data
OTHER [STATIC IMAGE] model
Sample: Drebrin monomer, 10 kDa Homo sapiens protein
Buffer: 17 mM NaH2PO4, 3 mM Na2HPO4, 50 mM NaCl, pH: 6
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Jul 7
Dynamic Interchange of Local Residue-Residue Interactions in the Largely Extended Single Alpha-Helix in Drebrin Biochemical Journal (2025)
Varga S, Péterfia B, Dudola D, Farkas V, Jeffries C, Permi P, Gáspári Z
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 18 nm3

SASDVW6 – Monomeric Adhesion-associated domain in MUC4 and Other Proteins (AMOP-domain) of Isthmin-1

UniProt ID: B1AKI9 (263-464) Isthmin-1 AMOP-domain
Isthmin-1 AMOP-domain experimental SAS data
Isthmin-1 AMOP-domain Kratky plot
Sample: Isthmin-1 AMOP-domain monomer, 25 kDa Homo sapiens protein
Buffer: 20 mM HEPES 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jun 21
Crystal structure of Isthmin-1 and reassessment of its functional role in pre-adipocyte signaling. Nat Commun 16(1):3580 (2025)
Li T, Stayrook SE, Li W, Wang Y, Li H, Zhang J, Liu Y, Klein DE
RgGuinier 2.3 nm
Dmax 9.7 nm
VolumePorod 45264 nm3

SASDVX6 – Monomeric Adhesion-associated domain in MUC4 and Other Proteins (AMOP-domain) of Isthmin-1, I455E, F458E douple mutant

UniProt ID: B1AKI9 (263-464) L-AMOP-IFEE
L-AMOP-IFEE experimental SAS data
L-AMOP-IFEE Kratky plot
Sample: L-AMOP-IFEE monomer, 25 kDa Homo sapiens protein
Buffer: 20 mM HEPES 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2023 Jun 21
Crystal structure of Isthmin-1 and reassessment of its functional role in pre-adipocyte signaling. Nat Commun 16(1):3580 (2025)
Li T, Stayrook SE, Li W, Wang Y, Li H, Zhang J, Liu Y, Klein DE
RgGuinier 2.4 nm
Dmax 8.8 nm
VolumePorod 46874 nm3

SASDV57 – Full-length SFPQ in high salt buffer

UniProt ID: P23246 (214-707) Splicing factor, proline- and glutamine-rich
Splicing factor, proline- and glutamine-rich experimental SAS data
Splicing factor, proline- and glutamine-rich Kratky plot
Sample: Splicing factor, proline- and glutamine-rich dimer, 153 kDa Homo sapiens protein
Buffer: 500mM KNO3, 20mM HEPES, 5% glycerol, 1mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2022 Oct 22
Structural dynamics of IDR interactions in human SFPQ and implications for liquid–liquid phase separation Acta Crystallographica Section D Structural Biology 81(7):357-379 (2025)
Koning H, Lai V, Sethi A, Chakraborty S, Ang C, Fox A, Duff A, Whitten A, Marshall A, Bond C
RgGuinier 7.9 nm
Dmax 42.5 nm
VolumePorod 485 nm3

SASDV67 – Human Splicing Factor Proline/Glutamine rich SFPQ1 dimer with C-terminal truncation (delta599-707)

UniProt ID: P23246 (1-598) Splicing Factor Proline/Glutamine rich (1-598)
Splicing Factor Proline/Glutamine rich (1-598) experimental SAS data
Splicing Factor Proline/Glutamine rich (1-598) Kratky plot
Sample: Splicing Factor Proline/Glutamine rich (1-598) dimer, 130 kDa Homo sapiens protein
Buffer: 500mM KNO3, 20mM HEPES, 5% glycerol, 1mM DTT, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2023 Mar 13
Structural dynamics of IDR interactions in human SFPQ and implications for liquid–liquid phase separation Acta Crystallographica Section D Structural Biology 81(7):357-379 (2025)
Koning H, Lai V, Sethi A, Chakraborty S, Ang C, Fox A, Duff A, Whitten A, Marshall A, Bond C
RgGuinier 7.6 nm
Dmax 34.3 nm
VolumePorod 400 nm3