Browse by DISSEMINATION: Published

SASDN77 – Truncated histone shaperone protein SET/TAF-Ib DC

SET nuclear proto-oncogene experimental SAS data
AMBER model
Sample: SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal (2022)
Casado-Combreras M, Rivero-Rodríguez F, Elena-Real C, Molodenskiy D, Díaz-Quintana A, Martinho M, Gerbaud G, González-Arzola K, Velázquez-Campoy A, Svergun D, Belle V, De la Rosa M, Díaz-Moreno I
RgGuinier 3.1 nm
Dmax 9.7 nm
VolumePorod 87 nm3

SASDN87 – Mixture 1:2 of truncated histone shaperone protein SET/TAF-Ib DC with cytochrome c

Cytochrome cSET nuclear proto-oncogene experimental SAS data
SASREF model
Sample: Cytochrome c dimer, 24 kDa Homo sapiens protein
SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ Computational and Structural Biotechnology Journal (2022)
Casado-Combreras M, Rivero-Rodríguez F, Elena-Real C, Molodenskiy D, Díaz-Quintana A, Martinho M, Gerbaud G, González-Arzola K, Velázquez-Campoy A, Svergun D, Belle V, De la Rosa M, Díaz-Moreno I
RgGuinier 4.2 nm
Dmax 16.0 nm

SASDMB5 – Leucine-rich repeat protein SHOC-2

Leucine-rich repeat protein SHOC-2 experimental SAS data
BILBOMD model
Sample: Leucine-rich repeat protein SHOC-2 monomer, 65 kDa Homo sapiens protein
Buffer: 25 mM Tris pH 7.5, 100 mM NaCl, 1 mM TCEP, 1 mM MnCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jun 20
Structural basis for SHOC2 modulation of RAS signalling. Nature (2022)
Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J
RgGuinier 3.2 nm
Dmax 11.2 nm
VolumePorod 85 nm3

SASDMC5 – Leucine-rich repeat protein SHOC-2 bound to serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP1C)

Leucine-rich repeat protein SHOC-2Serine/threonine-protein phosphatase PP1-gamma catalytic subunit experimental SAS data
BILBOMD model
Sample: Leucine-rich repeat protein SHOC-2 monomer, 65 kDa Homo sapiens protein
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit monomer, 37 kDa Homo sapiens protein
Buffer: 25 mM Tris pH 7.5, 100 mM NaCl, 1 mM TCEP, 1 mM MnCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jul 20
Structural basis for SHOC2 modulation of RAS signalling. Nature (2022)
Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J
RgGuinier 3.3 nm
Dmax 11.7 nm
VolumePorod 132 nm3

SASDMD5 – Leucine-rich repeat protein SHOC-2 bound to serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP1C) and GTPase KRas

Leucine-rich repeat protein SHOC-2Serine/threonine-protein phosphatase PP1-gamma catalytic subunitGTPase KRas experimental SAS data
BILBOMD model
Sample: Leucine-rich repeat protein SHOC-2 monomer, 65 kDa Homo sapiens protein
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit monomer, 37 kDa Homo sapiens protein
GTPase KRas monomer, 19 kDa Homo sapiens protein
Buffer: 25 mM Tris pH 7.5, 100 mM NaCl, 1 mM TCEP, 1 mM MnCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jul 20
Structural basis for SHOC2 modulation of RAS signalling. Nature (2022)
Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J
RgGuinier 3.3 nm
Dmax 11.7 nm
VolumePorod 156 nm3

SASDME5 – Leucine-rich repeat protein SHOC-2 bound to serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP1C) and Ras-related protein M-Ras

Leucine-rich repeat protein SHOC-2Serine/threonine-protein phosphatase PP1-gamma catalytic subunitRas-related protein M-Ras experimental SAS data
BILBOMD model
Sample: Leucine-rich repeat protein SHOC-2 monomer, 65 kDa Homo sapiens protein
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit monomer, 37 kDa Homo sapiens protein
Ras-related protein M-Ras monomer, 24 kDa Homo sapiens protein
Buffer: 25 mM Tris pH 7.5, 100 mM NaCl, 1 mM TCEP, 1 mM MnCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2020 Jul 20
Structural basis for SHOC2 modulation of RAS signalling. Nature (2022)
Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J
RgGuinier 3.5 nm
Dmax 12.4 nm
VolumePorod 215 nm3

SASDP43 – Accumulation-association protein (Aap) Brpt5.5 monomer

Accumulation associated protein experimental SAS data
Accumulation-association protein (Aap) Brpt5.5 monomer Rg histogram
Sample: Accumulation associated protein monomer, 78 kDa Staphylococcus epidermidis (strain … protein
Buffer: 50 mM MOPS, 50 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Oct 16
Solution structural studies of pre-amyloid oligomer states of the biofilm protein Aap. J Mol Biol :167708 (2022)
Yarawsky AE, Hopkins JB, Chatzimagas L, Hub JS, Herr AB
RgGuinier 14.7 nm
Dmax 55.8 nm

SASDP53 – Accumulation-association protein (Aap) Brpt5.5 5xH85A monomer

Accumulation associated protein (mutant) experimental SAS data
Accumulation-association protein (Aap) Brpt5.5 5xH85A monomer Rg histogram
Sample: Accumulation associated protein (mutant) monomer, 78 kDa Staphylococcus epidermidis (strain … protein
Buffer: 50 mM MOPS, 50 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 1
Solution structural studies of pre-amyloid oligomer states of the biofilm protein Aap. J Mol Biol :167708 (2022)
Yarawsky AE, Hopkins JB, Chatzimagas L, Hub JS, Herr AB
RgGuinier 14.1 nm
Dmax 57.2 nm

SASDP63 – Accumulation-association protein (Aap) Brpt5.5 2xH85A monomer

Accumulation associated protein (mutant) experimental SAS data
Accumulation-association protein (Aap) Brpt5.5 2xH85A monomer Rg histogram
Sample: Accumulation associated protein (mutant) monomer, 78 kDa Staphylococcus epidermidis (strain … protein
Buffer: 50 mM MOPS, 50 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 1
Solution structural studies of pre-amyloid oligomer states of the biofilm protein Aap. J Mol Biol :167708 (2022)
Yarawsky AE, Hopkins JB, Chatzimagas L, Hub JS, Herr AB
RgGuinier 14.4 nm
Dmax 56.6 nm

SASDP73 – Accumulation-association protein (Aap) Brpt5.5 5xH85A dimer in the presence of ZnCl2

Accumulation associated protein (mutant) experimental SAS data
PYMOL model
Sample: Accumulation associated protein (mutant) dimer, 155 kDa Staphylococcus epidermidis (strain … protein
Buffer: 50 mM MOPS, 50 mM NaCl, 5 mM ZnCl2, pH: 7.2
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2020 Mar 1
Solution structural studies of pre-amyloid oligomer states of the biofilm protein Aap. J Mol Biol :167708 (2022)
Yarawsky AE, Hopkins JB, Chatzimagas L, Hub JS, Herr AB
RgGuinier 15.0 nm
Dmax 63.3 nm