Browse by MODEL: Ab initio only

SASDJZ6 – Collagenase H C-terminal non-catalytic segments Polycystic Kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser, Tyr801Ser

Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser and Tyr801Ser) experimental SAS data
DAMFILT model
Sample: Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser and Tyr801Ser) monomer, 23 kDa Hathewaya histolytica protein
Buffer: 50 mM Tris, 1 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 5
Elucidating Collagen Degradation Synergy between Col G and Col H from Hathewaya (Clostridium) histolytica and Identifying novel structural features in HPT and REC domains from VarS histidine kinase in V. alginolyticus University of Arkansas PhD thesis 28030553 (2020)
Perry Caviness
RgGuinier 2.5 nm
Dmax 9.0 nm
VolumePorod 20 nm3

SASDJ27 – Collagenase H C-terminal non-catalytic segments Polycystic Kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser and Tyr801Ser bound to triple helical collagen like-peptide

Collagen like-peptide [GPRG(POG)13]Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser and Tyr801Ser) experimental SAS data
DAMFILT model
Sample: Collagen like-peptide [GPRG(POG)13] trimer, 11 kDa protein
Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) with Tyr780Ser, His782Ser, Tyr796Ser and Tyr801Ser) monomer, 23 kDa Hathewaya histolytica protein
Buffer: 50 mM HEPES, 100 mM NaCl, 5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 5
Elucidating Collagen Degradation Synergy between Col G and Col H from Hathewaya (Clostridium) histolytica and Identifying novel structural features in HPT and REC domains from VarS histidine kinase in V. alginolyticus University of Arkansas PhD thesis 28030553 (2020)
Perry Caviness
RgGuinier 3.2 nm
Dmax 18.0 nm
VolumePorod 34 nm3

SASDJ37 – Collagenase H C-terminal non-catalytic segments Polycystic Kidney disease domain 2 (PKD2) and Collagen binding domain (CBD) bound to triple helical collagen like-peptide

Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD))Collagen like-peptide [GPRG(POG)13] experimental SAS data
DAMFILT model
Sample: Collagenase ColH (Polycystic kidney disease domain 2 (PKD2) and Collagen binding domain (CBD)) monomer, 23 kDa Hathewaya histolytica protein
Collagen like-peptide [GPRG(POG)13] trimer, 11 kDa protein
Buffer: 50 mM HEPES, 100 mM NaCl, 5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 Mar 5
Elucidating Collagen Degradation Synergy between Col G and Col H from Hathewaya (Clostridium) histolytica and Identifying novel structural features in HPT and REC domains from VarS histidine kinase in V. alginolyticus University of Arkansas PhD thesis 28030553 (2020)
Perry Caviness
RgGuinier 3.3 nm
Dmax 18.0 nm
VolumePorod 35 nm3

SASDG75 – Pomacea diffusa perivitellin-1

Pomacea diffusa perivitellin-1 experimental SAS data
DAMMIF model
Sample: Pomacea diffusa perivitellin-1, 23 kDa Pomacea diffusa protein
Buffer: 50 mM Phosphate buffer, pH: 7.4
Experiment: SAXS data collected at SAXS2 Beamline, Brazilian Synchrotron Light Laboratory on 2015 Mar 27
A highly stable, non-digestible lectin from Pomacea diffusa unveils clade-related protection systems in apple snail eggs. J Exp Biol 223(Pt 19) (2020)
Brola TR, Dreon MS, Qiu JW, Heras H
RgGuinier 4.6 nm
Dmax 15.5 nm
VolumePorod 529 nm3

SASDHW2 – The Legionella pneumophila type II secretion system substrate NttE

Uncharacterized protein experimental SAS data
GASBOR model
Sample: Uncharacterized protein dimer, 66 kDa Legionella pneumophila protein
Buffer: 20 mM Tris, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Sep 18
Structure, Dynamics and Cellular Insight Into Novel Substrates of the Legionella pneumophila Type II Secretion System Frontiers in Molecular Biosciences 7 (2020)
Portlock T, Tyson J, Dantu S, Rehman S, White R, McIntire I, Sewell L, Richardson K, Shaw R, Pandini A, Cianciotto N, Garnett J
RgGuinier 2.9 nm
Dmax 9.4 nm
VolumePorod 114 nm3

SASDG47 – 2:4 heterohexamer of pUL7 and pUL51 from herpes simplex virus 1

Tegument protein UL7Tegument protein UL51 experimental SAS data
DAMMIN model
Sample: Tegument protein UL7 dimer, 68 kDa Human alphaherpesvirus 1 … protein
Tegument protein UL51 tetramer, 102 kDa Human alphaherpesvirus 1 … protein
Buffer: 20 mM HEPES, 200 mM NaCl, 3% (v/v) glycerol, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 16
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. Elife 9 (2020)
Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC
RgGuinier 4.6 nm
Dmax 19.7 nm
VolumePorod 340 nm3

SASDG57 – 1:2 heterotrimer of pUL7 and pUL51 from herpes simplex virus 1

Tegument protein UL7Tegument protein UL51 experimental SAS data
GASBOR model
Sample: Tegument protein UL7 monomer, 34 kDa Human alphaherpesvirus 1 … protein
Tegument protein UL51 dimer, 51 kDa Human alphaherpesvirus 1 protein
Buffer: 20 mM HEPES, 200 mM NaCl, 3% (v/v) glycerol, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 May 16
Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex. Elife 9 (2020)
Butt BG, Owen DJ, Jeffries CM, Ivanova L, Hill CH, Houghton JW, Ahmed MF, Antrobus R, Svergun DI, Welch JJ, Crump CM, Graham SC
RgGuinier 4.0 nm
Dmax 18.2 nm
VolumePorod 160 nm3

SASDH99 – Meiotic localizer of BRCA2 bound to BRME1 - MEILB2a1+2-BRME1 2:2 complex

BRME1Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: BRME1 dimer, 23 kDa Mus musculus protein
Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 5.0 nm
Dmax 19.0 nm
VolumePorod 104 nm3

SASDHA9 – Meiotic localizer of BRCA2 - MEILB2a1+2 dimer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 dimer, 26 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 4.6 nm
Dmax 16.0 nm
VolumePorod 88 nm3

SASDHB9 – Meiotic localizer of BRCA2 - MEILB2a1+2 octamer

Meiotic localizer of BRCA2 experimental SAS data
DAMMIF model
Sample: Meiotic localizer of BRCA2 octamer, 102 kDa Mus musculus protein
Buffer: 20 mM Tris pH 8.0, 150 mM KCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Oct 7
The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells Nature Communications 11(1) (2020)
Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, Guo R, Pendlebury D, Alam I, Livera G, Emmanuelle M, Wang P, Nandakumar J, Davies O, Shibuya H
RgGuinier 5.7 nm
Dmax 20.0 nm
VolumePorod 368 nm3