Browse by MODEL: Ensemble

SASDEN9 – HcpR transcriptional regulator of Porphyromonas gingivalis

Hcp Transcriptional regulator experimental SAS data
HcpR transcriptional regulator of Porphyromonas gingivalis Rg histogram
Sample: Hcp Transcriptional regulator dimer, 51 kDa Porphyromonas gingivalis protein
Buffer: 25 mM Tris 150 mM NaCl 1mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2014 Jan 24
Nitrosative stress sensing in Porphyromonas gingivalis: structure of and heme binding by the transcriptional regulator HcpR. Acta Crystallogr D Struct Biol 75(Pt 4):437-450 (2019)
Belvin BR, Musayev FN, Burgner J, Scarsdale JN, Escalante CR, Lewis JP
RgGuinier 2.9 nm
Dmax 10.5 nm
VolumePorod 76 nm3

SASDEP9 – Cyclic GMP-AMP synthase (cGAS)

Cyclic GMP-AMP synthase experimental SAS data
Cyclic GMP-AMP synthase (cGAS) Rg histogram
Sample: Cyclic GMP-AMP synthase monomer, 61 kDa Homo sapiens protein
Buffer: 20 mM HEPES, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity. EMBO Rep (2019)
Liu H, Moura-Alves P, Pei G, Mollenkopf HJ, Hurwitz R, Wu X, Wang F, Liu S, Ma M, Fei Y, Zhu C, Koehler AB, Oberbeck-Mueller D, Hahnke K, Klemm M, Guhlich-Bornhof U, Ge B, Tuukkanen A, Kolbe M, Dorhoi A, Kaufmann SH
RgGuinier 3.1 nm
Dmax 12.7 nm
VolumePorod 110 nm3

SASDEQ9 – Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP)

Cyclic GMP-AMP synthase2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine experimental SAS data
Cyclic GMP-AMP synthase (cGAS) with cyclic guanosine monophosphate–adenosine monophosphate (2'3'-cGAMP) Rg histogram
Sample: Cyclic GMP-AMP synthase dimer, 123 kDa Homo sapiens protein
2'-O,5'-O-((adenosine-3'-O,5'-O-diyl)bisphosphinico)guanosine dimer, 1 kDa
Buffer: 20 mM HEPES, pH: 7.4
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Apr 25
cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity. EMBO Rep (2019)
Liu H, Moura-Alves P, Pei G, Mollenkopf HJ, Hurwitz R, Wu X, Wang F, Liu S, Ma M, Fei Y, Zhu C, Koehler AB, Oberbeck-Mueller D, Hahnke K, Klemm M, Guhlich-Bornhof U, Ge B, Tuukkanen A, Kolbe M, Dorhoi A, Kaufmann SH
RgGuinier 3.9 nm
Dmax 14.1 nm
VolumePorod 127 nm3

SASDEL3 – The neutrophil cytosol factor 2 (p67phox) subunit of phagocyte NADPH oxidase

Neutrophil cytosol factor 2 experimental SAS data
The neutrophil cytosol factor 2 (p67phox) subunit of phagocyte NADPH oxidase Rg histogram
Sample: Neutrophil cytosol factor 2 monomer, 61 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, 5% glycerol, pH: 8
Experiment: SAXS data collected at D24, LURE on 2003 Apr 9
Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase. J Biol Chem (2019)
Ziegler CS, Bouchab L, Tramier M, Durand D, Fieschi F, Dupré-Crochet S, Mérola F, Nüße O, Erard M
RgGuinier 4.3 nm
Dmax 16.0 nm
VolumePorod 113 nm3

SASDEX7 – C-terminal truncated bank vole prion protein (amino acids 90-231) bound to Cu(II)

Major prion protein experimental SAS data
C-terminal truncated bank vole prion protein (amino acids 90-231) bound to Cu(II) Rg histogram
Sample: Major prion protein monomer, 16 kDa Myodes glareolus protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, 0.001 mM CuSO4, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Feb 25
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.2 nm
Dmax 8.7 nm
VolumePorod 30 nm3

SASDEY7 – C-terminal truncated ovine prion protein ARR (amino acids 94-234)

Major prion protein experimental SAS data
C-terminal truncated ovine prion protein ARR (amino acids 94-234) Rg histogram
Sample: Major prion protein monomer, 16 kDa Ovis aries protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 May 4
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.2 nm
Dmax 9.0 nm
VolumePorod 29 nm3

SASDEZ7 – C-terminal truncated ovine prion protein (94-234) with ARR polymorphism + Cu(II)

Major prion protein experimental SAS data
C-terminal truncated ovine prion protein (94-234) with ARR polymorphism + Cu(II) Rg histogram
Sample: Major prion protein monomer, 16 kDa Ovis aries protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, 0.001 mM CuSO4, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 May 4
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.2 nm
Dmax 8.8 nm
VolumePorod 31 nm3

SASDE28 – C-terminal truncated ovine prion protein (94-234) with VRQ polymorphism

Major prion protein experimental SAS data
C-terminal truncated ovine prion protein (94-234) with VRQ polymorphism Rg histogram
Sample: Major prion protein monomer, 16 kDa Ovis aries protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 May 4
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.1 nm
Dmax 9.1 nm
VolumePorod 29 nm3

SASDEW7 – C-terminal truncated bank vole prion protein (amino acids 90-231)

Major prion protein experimental SAS data
C-terminal truncated bank vole prion protein (amino acids 90-231) Rg histogram
Sample: Major prion protein monomer, 16 kDa Myodes glareolus protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Feb 25
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.3 nm
Dmax 9.4 nm
VolumePorod 29 nm3

SASDE38 – C-terminal truncated ovine prion protein (94-234) with VRQ polymorphism + Cu(II)

Major prion protein experimental SAS data
C-terminal truncated ovine prion protein (94-234) with VRQ polymorphism + Cu(II) Rg histogram
Sample: Major prion protein monomer, 16 kDa Ovis aries protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, 0.001 mM CuSO4, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 May 4
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.2 nm
Dmax 8.7 nm
VolumePorod 29 nm3