Browse by MODEL: Hybrid

SASDWK4 – Shewanella benthica hemoglobin

Group 1 truncated hemoglobin (C51S, C71S) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Group 1 truncated hemoglobin (C51S, C71S), 13 kDa Shewanella benthica KT99 protein
Buffer: 14 mM Tris, 6 mM potassium phosphate, pH: 7
Experiment: SAXS data collected at ID7A1 BioSAXS / HP-Bio Beamline, Cornell High Energy Synchrotron Source (CHESS) on 2022 May 1
Extremophilic hemoglobins: The structure of Shewanella benthica truncated hemoglobin N Journal of Biological Chemistry :108223 (2025)
Martinez Grundman J, Schultz T, Schlessman J, Johnson E, Gillilan R, Lecomte J
RgGuinier 1.8 nm
Dmax 5.8 nm
VolumePorod 30 nm3

SASDV64 – Serine hydrolase FphH with short chain esterase activity (Apo FphH)

Alpha/beta fold hydrolase experimental SAS data
DAMFILT model
Sample: Alpha/beta fold hydrolase monomer, 28 kDa Staphylococcus aureus protein
Buffer: 100 mM NaCl, 10 mM HEPES, pH: 7.6
Experiment: SAXS data collected at BioSAXS, Australian Synchrotron on 2024 Apr 11
Similar but Distinct—Biochemical Characterization of the Staphylococcus aureus Serine Hydrolases FphH  and FphI Proteins: Structure, Function, and Bioinformatics (2024)
Fellner M, Randall G, Bitac I, Warrender A, Sethi A, Jelinek R, Kass I
RgGuinier 2.1 nm
Dmax 6.5 nm
VolumePorod 41 nm3

SASDMV7 – The tetramer of splicing factor, proline- and glutamine-rich and Non-POU domain-containing octamer-binding protein (SFPQ214-598(R542C)/NONO53-312)

Splicing factor, proline- and glutamine-richNon-POU domain-containing octamer-binding protein experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Splicing factor, proline- and glutamine-rich dimer, 153 kDa Homo sapiens protein
Non-POU domain-containing octamer-binding protein dimer, 60 kDa Homo sapiens protein
Buffer: 20 mM Tris, 250 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 18
Structural plasticity of the coiled-coil interactions in human SFPQ. Nucleic Acids Res (2024)
Koning HJ, Lai JY, Marshall AC, Stroeher E, Monahan G, Pullakhandam A, Knott GJ, Ryan TM, Fox AH, Whitten A, Lee M, Bond CS
RgGuinier 5.5 nm
Dmax 20.4 nm
VolumePorod 304 nm3

SASDMW7 – Concentration dependent dimer-tetramer transition of splicing factor, proline- and glutamine-rich with Non-POU domain-containing octamer-binding protein (SFPQ276-565/NONO53-312)

Splicing factor, proline- and glutamine-rich (276-565)Non-POU domain-containing octamer-binding protein (53-312) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Splicing factor, proline- and glutamine-rich (276-565) monomer, 34 kDa Homo sapiens protein
Non-POU domain-containing octamer-binding protein (53-312) monomer, 30 kDa Homo sapiens protein
Buffer: 20 mM Tris, 250 mM NaCl, pH: 7.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Apr 28
Structural plasticity of the coiled-coil interactions in human SFPQ. Nucleic Acids Res (2024)
Koning HJ, Lai JY, Marshall AC, Stroeher E, Monahan G, Pullakhandam A, Knott GJ, Ryan TM, Fox AH, Whitten A, Lee M, Bond CS
RgGuinier 3.0 nm
Dmax 12.7 nm
VolumePorod 102 nm3

SASDVG6 – 2-nitroimidazole nitrohydrolase

2-nitroimidazole nitrohydrolase (T2I, G14D, K73R) experimental SAS data
REFMAC model
Sample: 2-nitroimidazole nitrohydrolase (T2I, G14D, K73R) hexamer, 258 kDa Mycobacterium sp. (strain … protein
Buffer: 25 mM Tris-HCl, 150 mM NaCl, 5% (v/v) glycerol, pH: 7.6
Experiment: SAXS data collected at BioSAXS, Australian Synchrotron on 2024 Aug 6
Structural insights into the enzymatic breakdown of azomycin-derived antibiotics by 2-nitroimdazole hydrolase (NnhA). Commun Biol 7(1):1676 (2024)
Ahmed FH, Liu JW, Royan S, Warden AC, Esquirol L, Pandey G, Newman J, Scott C, Peat TS
RgGuinier 4.6 nm
Dmax 12.6 nm
VolumePorod 363 nm3

SASDQJ7 – Alpha Synuclein at 283 K and concentration of 8 mg/ml

Human alpha-synuclein experimental SAS data
ALPHAFOLD model
Sample: Human alpha-synuclein monomer, 14 kDa Homo sapiens protein
Buffer: 10 mM HEPES, 50 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2015 Mar 18
Visualizing gaussian-chain like structural models of human α-synuclein in monomeric pre-fibrillar state: Solution SAXS data and modeling analysis. Int J Biol Macromol 288:138614 (2024)
Dey M, Gupta A, Badmalia MD, Ashish, Sharma D
RgGuinier 4.7 nm
Dmax 17.6 nm
VolumePorod 81 nm3

SASDVQ6 – Retriever complex

VPS35 endosomal protein-sorting factor-likeVacuolar protein sorting-associated protein 29Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: VPS35 endosomal protein-sorting factor-like monomer, 110 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 29 monomer, 21 kDa Homo sapiens protein
Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 200 mM NaCl, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Apr 28
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 5.2 nm
Dmax 21.5 nm
VolumePorod 256 nm3

SASDVR6 – Vacuolar protein sorting-associated protein 26C (VPS26C)

Vacuolar protein sorting-associated protein 26C experimental SAS data
ALPHAFOLD model
Sample: Vacuolar protein sorting-associated protein 26C monomer, 33 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl, 1 mM TCEP,, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Apr 22
Selective cargo and membrane recognition by SNX17 regulates its interaction with Retriever EMBO Reports (2024)
Martín-González A, Méndez-Guzmán I, Zabala-Zearreta M, Quintanilla A, García-López A, Martínez-Lombardía E, Albesa-Jové D, Acosta J, Lucas M
RgGuinier 2.7 nm
Dmax 9.4 nm
VolumePorod 44 nm3

SASDU78 – Trypanosoma brucei ESAG4 membrane-proximal Venus Fly Trap domain 2 (VFT2)

adenylate cyclase experimental SAS data
ALPHAFOLD model
Sample: Adenylate cyclase monomer, 43 kDa Trypanosoma brucei protein
Buffer: 50 mM Tris-HCl, 500 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2023 Sep 23
Biophysical analysis of the membrane-proximal Venus Flytrap domain of ESAG4 receptor-like adenylate cyclase from Trypanosoma brucei. Mol Biochem Parasitol 260:111653 (2024)
Alves DO, Geens R, da Silva Arruda HR, Jennen L, Corthaut S, Wuyts E, de Andrade GC, Prosdocimi F, Cordeiro Y, Pires JR, Vieira LR, de Oliveira GAP, Sterckx YG, Salmon D
RgGuinier 2.3 nm
Dmax 7.6 nm
VolumePorod 76 nm3

SASDVH7 – Third double-stranded RNA-binding domain of Human Double-stranded RNA-specific adenosine deaminase (ADAR1) (residues 716-797, i.e. dsRBD3-short)

Third double-stranded RNA-binding domain of human ADAR1 (residues 716-797, i.e. dsRBD3-short) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Third double-stranded RNA-binding domain of human ADAR1 (residues 716-797, i.e. dsRBD3-short) dimer, 18 kDa Homo sapiens protein
Buffer: 20 mM Na-HEPES, 55 mM KOAc, 10 mM NaCl, 1 mM TCEP, pH: 7.3
Experiment: SAXS data collected at SWING, SOLEIL on 2020 Jun 27
Dimerization of ADAR1 modulates site-specificity of RNA editing Nature Communications 15(1) (2024)
Mboukou A, Rajendra V, Messmer S, Mandl T, Catala M, Tisné C, Jantsch M, Barraud P
RgGuinier 1.9 nm
Dmax 5.5 nm
VolumePorod 27 nm3