|
|
|
|
|
| Sample: |
Histone deacetylase 5 monomer, 51 kDa Homo sapiens protein
|
| Buffer: |
25 mM HEPES, 150 mM KCl, 1 mM DTT,, pH: 7.5 |
| Experiment: |
SAXS
data collected at Xenocs Xeuss 2.0 Q-Xoom, Center for Structural Studies, Heinrich-Heine-University on 2024 Feb 29
|
In vitro characterization of the catalytic domain of human histone deacetylase 5
Scientific Reports (2026)
Mammen C, Hornung F, Anzenhofer C, Schumacher J, Reiners J, Li J, Mazzone F, Bilsing F, Kassack M, Kurz T, Smits S
|
| RgGuinier |
2.8 |
nm |
| Dmax |
10.1 |
nm |
| VolumePorod |
82 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
N-myc proto-oncogene protein, residues 1-69 monomer, 8 kDa Homo sapiens protein
|
| Buffer: |
20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Nov 28
|
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
|
| RgGuinier |
2.4 |
nm |
| Dmax |
11.0 |
nm |
| VolumePorod |
12 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
N-myc proto-oncogene protein, residues 1-100 monomer, 11 kDa Homo sapiens protein
|
| Buffer: |
20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Nov 28
|
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
|
| RgGuinier |
3.0 |
nm |
| Dmax |
13.0 |
nm |
| VolumePorod |
22 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Aurora kinase A mutant C290A:C393A monomer, 33 kDa Homo sapiens protein
|
| Buffer: |
20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Nov 28
|
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
|
| RgGuinier |
2.2 |
nm |
| Dmax |
9.5 |
nm |
| VolumePorod |
59 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
N-myc proto-oncogene protein, residues 1-69 monomer, 8 kDa Homo sapiens protein
Aurora kinase A mutant C290A:C393A monomer, 33 kDa Homo sapiens protein
|
| Buffer: |
20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Nov 28
|
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
|
| RgGuinier |
2.5 |
nm |
| Dmax |
10.2 |
nm |
| VolumePorod |
62 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
N-myc proto-oncogene protein, residues 1-100 monomer, 11 kDa Homo sapiens protein
Aurora kinase A mutant C290A:C393A monomer, 33 kDa Homo sapiens protein
|
| Buffer: |
20mM HEPES, 150mM NaCl, 5mM MgCl2, 3% v/v glycerol, 2mM TCEP, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2022 Dec 9
|
The N-Myc MB0-MBI region interacts specifically and dynamically with the N-lobe of Aurora kinase A.
Nat Commun (2026)
Hultman J, Morad V, Tanner E, Kenney TMG, Pietras Z, Khare LP, Derbyshire D, Resetca D, Arrowsmith CH, Aili D, Ekström S, Penn LZ, Wallner B, Ahlner A, Sunnerhagen M
|
| RgGuinier |
2.8 |
nm |
| Dmax |
11.4 |
nm |
| VolumePorod |
82 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
14-3-3 protein eta dimer, 57 kDa Homo sapiens protein
|
| Buffer: |
20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 1 mM EDTA, 3% glycerol, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Dec 4
|
Molecular basis of the regulation of full-length Nedd4-2 through calcium and 14-3-3 proteins
Veronika Obšilová
|
| RgGuinier |
2.9 |
nm |
| Dmax |
8.4 |
nm |
| VolumePorod |
85 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
14-3-3 protein eta dimer, 57 kDa Homo sapiens protein
Isoform 5 of E3 ubiquitin-protein ligase NEDD4-like monomer, 110 kDa Homo sapiens protein
|
| Buffer: |
20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 1 mM CaCl2, 3% glycerol, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL P12, PETRA III on 2023 Dec 4
|
Molecular basis of the regulation of full-length Nedd4-2 through calcium and 14-3-3 proteins
Veronika Obšilová
|
| RgGuinier |
5.5 |
nm |
| Dmax |
23.5 |
nm |
| VolumePorod |
290 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
La-related protein 6 monomer, 27 kDa Homo sapiens protein
|
| Buffer: |
25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT, pH: 7.5 |
| Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2024 Oct 1
|
An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.
Nat Commun (2026)
Capraro F, Abis G, Incocciati A, Simpson PJ, Karimzadeh M, Masino L, Barley A, Bui TTT, Kelly G, Goodarzi H, Conte MR, Mardakheh FK
|
| RgGuinier |
2.9 |
nm |
| Dmax |
8.3 |
nm |
| VolumePorod |
59 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
La-related protein 6 monomer, 34 kDa Homo sapiens protein
|
| Buffer: |
25 mM Tris-HCl, 100 mM KCl, 5 mM MgCl2, 1 mM DTT, pH: 7.5 |
| Experiment: |
SAXS
data collected at B21, Diamond Light Source on 2024 Oct 1
|
An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6.
Nat Commun (2026)
Capraro F, Abis G, Incocciati A, Simpson PJ, Karimzadeh M, Masino L, Barley A, Bui TTT, Kelly G, Goodarzi H, Conte MR, Mardakheh FK
|
| RgGuinier |
3.6 |
nm |
| Dmax |
15.0 |
nm |
| VolumePorod |
138 |
nm3 |
|
|