Browse by MODEL: No model

SASDU42 – HIV-1 Envelope Glycoprotein SOSIP from a BG505 isolate containing T332N mutation at 25 °C

BG505SOSIP.664T332N Env glycoprotein experimental SAS data
BG505SOSIP.664T332N Env glycoprotein Kratky plot
Sample: BG505SOSIP.664T332N Env glycoprotein trimer, 213 kDa HIV-1 group M protein
Buffer: 15 mM HEPES, 150 mM NaCl, pH: 7.1
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2017 Jun 1
Microsecond dynamics control the HIV-1 Envelope conformation. Sci Adv 10(5):eadj0396 (2024)
Bennett AL, Edwards R, Kosheleva I, Saunders C, Bililign Y, Williams A, Bubphamala P, Manosouri K, Anasti K, Saunders KO, Alam SM, Haynes BF, Acharya P, Henderson R
RgGuinier 5.0 nm
Dmax 20.7 nm
VolumePorod 712 nm3

SASDQF9 – GRP94 protein (Endoplasmin)

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
Sun S, Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.6 nm
Dmax 24.0 nm
VolumePorod 260 nm3

SASDQG9 – GRP94 protein (Endoplasmin) bound to ADP

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
Sun S, Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.7 nm
Dmax 24.0 nm
VolumePorod 274 nm3

SASDQH9 – GRP94 protein (Endoplasmin) bound to AMP-PNP

Endoplasmin experimental SAS data
Endoplasmin Kratky plot
Sample: Endoplasmin dimer, 169 kDa Mus musculus protein
Buffer: 25 mM HEPES, 200 mM NaCl, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2018 Jul 11
Visualization of conformational transition of GRP94 in solution. Life Sci Alliance 7(2) (2024)
Sun S, Zhu R, Zhu M, Wang Q, Li N, Yang B
RgGuinier 5.5 nm
Dmax 24.5 nm
VolumePorod 260 nm3

SASDRD8 – Drosophila melanogaster kinesin heavy chain

Kinesin heavy chain (A515T) experimental SAS data
Kinesin heavy chain (A515T) Kratky plot
Sample: Kinesin heavy chain (A515T) dimer, 221 kDa Drosophila melanogaster protein
Buffer: 25 mM HEPES/KOH, 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, pH: 7.3
Experiment: SAXS data collected at BM29, ESRF on 2022 Feb 19
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport. Nat Struct Mol Biol (2024)
Heber S, McClintock MA, Simon B, Mehtab E, Lapouge K, Hennig J, Bullock SL, Ephrussi A
RgGuinier 10.0 nm
Dmax 45.0 nm
VolumePorod 920 nm3

SASDRE8 – Drosophila melanogaster kinesin heavy chain + Tropomyosin1-I/C

Kinesin heavy chain (A515T)GH09289p experimental SAS data
Kinesin heavy chain (A515T) GH09289p Kratky plot
Sample: Kinesin heavy chain (A515T) dimer, 221 kDa Drosophila melanogaster protein
GH09289p dimer, 96 kDa Drosophila melanogaster protein
Buffer: 25 mM HEPES/KOH, 150 mM NaCl, 1 mM MgCl2, 2 mM DTT, pH: 7.3
Experiment: SAXS data collected at BM29, ESRF on 2022 Feb 19
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport. Nat Struct Mol Biol (2024)
Heber S, McClintock MA, Simon B, Mehtab E, Lapouge K, Hennig J, Bullock SL, Ephrussi A
RgGuinier 8.7 nm
Dmax 45.0 nm
VolumePorod 840 nm3

SASDTP2 – Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) wild type

Ubiquitin carboxyl-terminal hydrolase isozyme L1 experimental SAS data
Ubiquitin carboxyl-terminal hydrolase isozyme L1 Kratky plot
Sample: Ubiquitin carboxyl-terminal hydrolase isozyme L1 monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.03% NaN3, pH: 7.5
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Sep 2
Altered protein dynamics and a more reactive catalytic cysteine in a neurodegeneration-associated UCHL1 mutant. J Mol Biol :168438 (2024)
Kenny S, Lai CH, Chiang TS, Brown K, Hewitt CS, Krabill AD, Chang HT, Wang YS, Flaherty DP, Danny Hsu ST, Das C
RgGuinier 1.9 nm
Dmax 5.9 nm
VolumePorod 26 nm3

SASDTQ2 – Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) R178Q mutant

Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) experimental SAS data
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) Kratky plot
Sample: Ubiquitin carboxyl-terminal hydrolase isozyme L1 (R178Q) monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.03% NaN3, pH: 7.5
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Sep 2
Altered protein dynamics and a more reactive catalytic cysteine in a neurodegeneration-associated UCHL1 mutant. J Mol Biol :168438 (2024)
Kenny S, Lai CH, Chiang TS, Brown K, Hewitt CS, Krabill AD, Chang HT, Wang YS, Flaherty DP, Danny Hsu ST, Das C
RgGuinier 1.9 nm
Dmax 5.8 nm
VolumePorod 25 nm3

SASDTW2 – Protein phosphatase 2A (PP2A)-B56δ holoenzyme wildtype

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformIsoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H)Isoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform experimental SAS data
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Isoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H) Isoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Kratky plot
Sample: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform monomer, 65 kDa Homo sapiens protein
Isoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H) monomer, 70 kDa Homo sapiens protein
Isoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform monomer, 36 kDa Homo sapiens protein
Buffer: 25 mM Tris, 150 mM NaCl, 50 µM MnCl2, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 20
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc Natl Acad Sci U S A 121(1):e2310727120 (2024)
Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, Suzuki A, Huang X, Strack S, Xing Y
RgGuinier 4.0 nm
Dmax 12.0 nm
VolumePorod 266 nm3

SASDTX2 – Protein phosphatase 2A (PP2A)-B56δ holoenzyme E198K mutant

Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformIsoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoformIsoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H, E198K) experimental SAS data
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform Isoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Isoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H, E198K) Kratky plot
Sample: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform monomer, 65 kDa Homo sapiens protein
Isoform 1 of Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform monomer, 36 kDa Homo sapiens protein
Isoform Delta-1 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (R160H, E198K) monomer, 70 kDa Homo sapiens protein
Buffer: 25 mM Tris, 150 mM NaCl, 50 µM MnCl2, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Nov 20
B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations. Proc Natl Acad Sci U S A 121(1):e2310727120 (2024)
Wu CG, Balakrishnan VK, Merrill RA, Parihar PS, Konovolov K, Chen YC, Xu Z, Wei H, Sundaresan R, Cui Q, Wadzinski BE, Swingle MR, Musiyenko A, Chung WK, Honkanen RE, Suzuki A, Huang X, Strack S, Xing Y
RgGuinier 4.2 nm
Dmax 14.0 nm
VolumePorod 305 nm3