|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
10.7 |
nm |
| VolumePorod |
326 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
10.7 |
nm |
| VolumePorod |
315 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.7 |
nm |
| Dmax |
10.3 |
nm |
| VolumePorod |
237 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
10.8 |
nm |
| VolumePorod |
238 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
10.6 |
nm |
| VolumePorod |
255 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.7 |
nm |
| Dmax |
11.3 |
nm |
| VolumePorod |
256 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
11.4 |
nm |
| VolumePorod |
260 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399D , 56 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.9 |
nm |
| Dmax |
10.6 |
nm |
| VolumePorod |
272 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399G , 55 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.8 |
nm |
| Dmax |
11.3 |
nm |
| VolumePorod |
290 |
nm3 |
|
|
|
|
|
|
|
| Sample: |
Alpha-aminoadipic semialdehyde dehydrogenase E399G , 55 kDa Homo sapiens protein
|
| Buffer: |
50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
|
| Experiment: |
SAXS
data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
|
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy.
J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
|
| RgGuinier |
3.7 |
nm |
| Dmax |
10.6 |
nm |
| VolumePorod |
250 |
nm3 |
|
|
