Browse by MACROMOLECULE type: protein

SASDXX6 – Angiotensin converting Enzyme 2 bound to Receptor binding domain

Receptor Binding DomainAngiotensin converting Enzyme 2 experimental SAS data
Receptor Binding Domain Angiotensin converting Enzyme 2 Kratky plot
Sample: Receptor Binding Domain monomer, 25 kDa Severe acute respiratory … protein
Angiotensin converting Enzyme 2 monomer, 92 kDa Homo sapiens protein
Buffer: 50mM Tris, 200mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2021 Jul 29
ACE2 RBD Complex
Raja Tripathi
RgGuinier 6.7 nm
Dmax 21.4 nm
VolumePorod 783 nm3

SASDXY6 – M protease of SARS CoV-2 with JL-352 compound

3 Chymotrypsin Like Protease experimental SAS data
3 Chymotrypsin Like Protease Kratky plot
Sample: 3 Chymotrypsin Like Protease dimer, 68 kDa Severe acute respiratory … protein
Buffer: 50mM Tris, 200mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2021 Mar 26
M protease SARS CoV-2 with JL-352
Raja Tripathi
RgGuinier 4.7 nm
Dmax 12.3 nm
VolumePorod 271 nm3

SASDXZ6 – Receptor Binding Domain of SARS CoV-2

Receptor Binding Domain of SARS CoV-2 experimental SAS data
Receptor Binding Domain of SARS CoV-2 Kratky plot
Sample: Receptor Binding Domain of SARS CoV-2 monomer, 25 kDa protein
Buffer: 50mM Tris, 200mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2021 Jul 29
Receptor Binding Domain of SARS CoV-2
Raja Tripathi
RgGuinier 2.9 nm
Dmax 6.1 nm
VolumePorod 52 nm3

SASDYG7 – Angiotensin-converting Enzyme 2 with Spike glycoprotein Receptor binding domain, along with Umifenovir compound

Angiotensin-converting enzyme 2Spike glycoprotein experimental SAS data
Angiotensin-converting enzyme 2 Spike glycoprotein Kratky plot
Sample: Angiotensin-converting enzyme 2 hexamer, 555 kDa Homo sapiens protein
Spike glycoprotein hexamer, 150 kDa Severe acute respiratory … protein
Buffer: 50mM Tris, 150mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2021 Oct 21
ACE 2 RBD
Raja Tripathi
RgGuinier 4.4 nm
Dmax 11.4 nm

SASDZZ5 – C-type lectin mosGCTL-3 from Aedes aegypti, ~0.3 mg/ml

mosGCTL-3 experimental SAS data
mosGCTL-3 Kratky plot
Sample: MosGCTL-3 dimer, 36 kDa Aedes aegypti protein
Buffer: 20 mM Tris, 250 mM NaCl, 2.5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Dec 17
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm

SASDZ26 – C-type lectin mosGCTL-3 from Aedes aegypti, ~0.2 mg/ml

mosGCTL-3 experimental SAS data
mosGCTL-3 Kratky plot
Sample: MosGCTL-3 dimer, 36 kDa Aedes aegypti protein
Buffer: 20 mM Tris, 250 mM NaCl, 2.5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Dec 17
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm

SASDZ56 – C-type lectin mosGCTL-1 from Aedes aegypti, ~0.6 mg/ml

C-type lectin mosGCTL-1 experimental SAS data
C-type lectin mosGCTL-1 from Aedes aegypti, ~0.6 mg/ml Rg histogram
Sample: C-type lectin mosGCTL-1 dimer, 35 kDa Aedes aegypti protein
Buffer: 25 mM Citrate, 1 M NaCl, 10 mM CaCl2, pH: 4
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Aug 7
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm

SASDZ66 – C-type lectin mosGCTL-1 from Aedes aegypti, ~0.8 mg/ml

C-type lectin mosGCTL-1 experimental SAS data
C-type lectin mosGCTL-1 from Aedes aegypti, ~0.8 mg/ml Rg histogram
Sample: C-type lectin mosGCTL-1 dimer, 35 kDa Aedes aegypti protein
Buffer: 25 mM Citrate, 1 M NaCl, 10 mM CaCl2, pH: 4
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Aug 7
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm

SASDZ76 – C-type lectin mosGCTL-1 from Aedes aegypti, ~1.0 mg/ml

C-type lectin mosGCTL-1 experimental SAS data
C-type lectin mosGCTL-1 from Aedes aegypti, ~1.0 mg/ml Rg histogram
Sample: C-type lectin mosGCTL-1 dimer, 35 kDa Aedes aegypti protein
Buffer: 25 mM Citrate, 1 M NaCl, 10 mM CaCl2, pH: 4
Experiment: SAXS data collected at B21, Diamond Light Source on 2017 Aug 7
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm

SASDZ86 – C-type lectin mosGCTL-3 from Aedes aegypti, ~0.45 mg/ml

mosGCTL-3 experimental SAS data
C-type lectin mosGCTL-3 from Aedes aegypti, ~0.45 mg/ml Rg histogram
Sample: MosGCTL-3 dimer, 36 kDa Aedes aegypti protein
Buffer: 20 mM Tris, 250 mM NaCl, 2.5 mM CaCl2, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Dec 17
Conserved dimerization architecture in C-type lectins from virus-vector mosquitoes
Max Renner
RgGuinier 2.4 nm