SASBDB entries for UniProt ID:

SASDVA4 – β-Antigen C Protein B6C domain bound to Leukocyte Immunoglobulin-Like Receptor LILR-B3

UniProt ID: P27951 (258-428) IgA FC receptor

UniProt ID: A0A0G2JM46 (24-443) Leukocyte immunoglobulin-like receptor subfamily B member 3 (P288R)
IgA FC receptorLeukocyte immunoglobulin-like receptor subfamily B member 3 (P288R) experimental SAS data
MULTIFOXS model
Sample: IgA FC receptor monomer, 20 kDa Streptococcus agalactiae protein
Leukocyte immunoglobulin-like receptor subfamily B member 3 (P288R) monomer, 47 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 300 mM NaCl, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Nov 17
Bacterial targeting of the neutrophil inhibitory receptor LILRB3 to evade antibody immunity
Ying Zhang
RgGuinier 3.9 nm
Dmax 13.5 nm
VolumePorod 202 nm3

SASDVB4 – β-Antigen C Protein B75KN-CTD domain bound to Leukocyte Immunoglobulin-Like Receptor LILR-B3

UniProt ID: A0A0G2JM46 (24-443) Leukocyte immunoglobulin-like receptor subfamily B member 3 (P288R)

UniProt ID: P27951 (725-826) IgA FC receptor (N770H)
Leukocyte immunoglobulin-like receptor subfamily B member 3 (P288R)IgA FC receptor (N770H) experimental SAS data
MULTIFOXS model
Sample: Leukocyte immunoglobulin-like receptor subfamily B member 3 (P288R) monomer, 47 kDa Homo sapiens protein
IgA FC receptor (N770H) monomer, 12 kDa Streptococcus agalactiae protein
Buffer: 20 mM HEPES, 300 mM NaCl, pH: 7.4
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Nov 17
Bacterial targeting of the neutrophil inhibitory receptor LILRB3 to evade antibody immunity
Ying Zhang
RgGuinier 3.9 nm
Dmax 14.1 nm
VolumePorod 175 nm3

SASDVC4 – Shwachman-Bodian-Diamond syndrome protein (SBDS) - wild type

UniProt ID: Q9Y3A5 (1-250) Ribosome maturation protein SBDS
Ribosome maturation protein SBDS experimental SAS data
MULTIFOXS model
Sample: Ribosome maturation protein SBDS monomer, 29 kDa Homo sapiens protein
Buffer: 50 mM Tris pH 8.0, 10% glycerol, 300 mM NaCl, 5 mM MgCl2., pH:
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Apr 6
Structural Implications of Missense Point Mutations in Shwachman–Bodian–Diamond Syndrome Protein (SBDS): A Combined SAXS/MD Investigation ACS Omega (2025)
Mattiotti G, Nanna V, Giulini M, Alberga D, Mangiatordi G, Sánchez-Puig N, Saviano M, Tubiana L, Potestio R, Lattanzi G, Siliqi D
RgGuinier 3.0 nm
Dmax 11.4 nm
VolumePorod 50 nm3

SASDVD4 – Shwachman-Bodian-Diamond syndrome protein (SBDS) - R19Q mutant

UniProt ID: Q9Y3A5 (1-250) Ribosome maturation protein SBDS (R19Q)
Ribosome maturation protein SBDS (R19Q) experimental SAS data
MULTIFOXS model
Sample: Ribosome maturation protein SBDS (R19Q) monomer, 29 kDa Homo sapiens protein
Buffer: 50 mM Tris pH 8.0, 10% glycerol, 300 mM NaCl, 5 mM MgCl2., pH:
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Apr 6
Structural Implications of Missense Point Mutations in Shwachman–Bodian–Diamond Syndrome Protein (SBDS): A Combined SAXS/MD Investigation ACS Omega (2025)
Mattiotti G, Nanna V, Giulini M, Alberga D, Mangiatordi G, Sánchez-Puig N, Saviano M, Tubiana L, Potestio R, Lattanzi G, Siliqi D
RgGuinier 2.9 nm
Dmax 12.2 nm
VolumePorod 46 nm3

SASDVE4 – Shwachman-Bodian-Diamond syndrome protein (SBDS) - I167T mutant

UniProt ID: Q9Y3A5 (1-250) Ribosome maturation protein SBDS (I167T)
Ribosome maturation protein SBDS (I167T) experimental SAS data
MULTIFOXS model
Sample: Ribosome maturation protein SBDS (I167T) monomer, 29 kDa Homo sapiens protein
Buffer: 50 mM Tris pH 8.0, 10% glycerol, 300 mM NaCl, 5 mM MgCl2., pH:
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Apr 6
Structural Implications of Missense Point Mutations in Shwachman–Bodian–Diamond Syndrome Protein (SBDS): A Combined SAXS/MD Investigation ACS Omega (2025)
Mattiotti G, Nanna V, Giulini M, Alberga D, Mangiatordi G, Sánchez-Puig N, Saviano M, Tubiana L, Potestio R, Lattanzi G, Siliqi D
RgGuinier 2.9 nm
Dmax 10.5 nm
VolumePorod 44 nm3

SASDVF4 – Shwachman-Bodian-Diamond syndrome protein (SBDS) - R175W mutant

UniProt ID: Q9Y3A5 (1-250) Ribosome maturation protein SBDS (R175W)
Ribosome maturation protein SBDS (R175W) experimental SAS data
MULTIFOXS model
Sample: Ribosome maturation protein SBDS (R175W) monomer, 29 kDa Homo sapiens protein
Buffer: 50 mM Tris pH 8.0, 10% glycerol, 300 mM NaCl, 5 mM MgCl2., pH:
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Apr 6
Structural Implications of Missense Point Mutations in Shwachman–Bodian–Diamond Syndrome Protein (SBDS): A Combined SAXS/MD Investigation ACS Omega (2025)
Mattiotti G, Nanna V, Giulini M, Alberga D, Mangiatordi G, Sánchez-Puig N, Saviano M, Tubiana L, Potestio R, Lattanzi G, Siliqi D
RgGuinier 3.1 nm
Dmax 11.6 nm
VolumePorod 48 nm3

SASDVR4 – Endophilin B1 wild type (0.69 mg/ml)

UniProt ID: Q9Y371 (1-365) Endophilin-B1
Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 dimer, 82 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 5.1 nm
Dmax 16.0 nm
VolumePorod 151 nm3

SASDVS4 – Endophilin B1 wild type (0.34mg/ml)

UniProt ID: Q9Y371 (1-365) Endophilin-B1
Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 dimer, 82 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 5.0 nm
Dmax 16.0 nm
VolumePorod 152 nm3

SASDVT4 – Endophilin B1 wild type (0.14 mg/ml)

UniProt ID: Q9Y371 (1-365) Endophilin-B1
Endophilin-B1 experimental SAS data
Sample: Endophilin-B1 monomer, 41 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 3.7 nm
Dmax 15.3 nm
VolumePorod 47 nm3

SASDVU4 – Endophilin B1 truncated construction without SH3 domain

UniProt ID: Q9Y371 (1-306) Endophilin-B1 (Δ307-360)
Endophilin-B1 (Δ307-360) experimental SAS data
Sample: Endophilin-B1 (Δ307-360) dimer, 68 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM TCEP, 0.5 mM DTT, pH: 8.1
Experiment: SAXS data collected at BM29, ESRF on 2024 Mar 10
Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers Communications Biology 8(1) (2025)
Thorlacius A, Rulev M, Sundberg O, Sundborger-Lunna A
RgGuinier 4.6 nm
Dmax 15.2 nm
VolumePorod 149 nm3