SASBDB entries for UniProt ID:

SASDX52 – Fatty acyl-CoA synthetase FadD5

UniProt ID: O07411 (1-554) Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase)
Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) experimental SAS data
ALPHAFOLD model
Sample: Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) dimer, 123 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM HEPES, 500 mM NaCl, 5 mM MgCl2, 1 mM β-mercaptoethanol, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Oct 20
Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis. Biochem Biophys Res Commun 769:151960 (2025)
Rahman MA, Dalwani S, Venkatesan R
RgGuinier 3.6 nm
Dmax 12.3 nm
VolumePorod 221 nm3

SASDX62 – Fatty acyl-CoA synthetase FadD5 with 2 mM ATP

UniProt ID: O07411 (1-554) Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase)
Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) experimental SAS data
ALPHAFOLD model
Sample: Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) dimer, 123 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM HEPES, 500 mM NaCl, 5 mM MgCl2, 1 mM β-mercaptoethanol, 2mM ATP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Oct 20
Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis. Biochem Biophys Res Commun 769:151960 (2025)
Rahman MA, Dalwani S, Venkatesan R
RgGuinier 3.6 nm
Dmax 12.1 nm
VolumePorod 213 nm3

SASDX72 – Fatty acyl-CoA synthetase FadD5 with 2 mM coenzyme A (CoA)

UniProt ID: O07411 (1-554) Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase)
Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) experimental SAS data
ALPHAFOLD model
Sample: Probable fatty-acid-CoA ligase FadD5 (Fatty-acid-CoA synthetase) (Fatty-acid-CoA synthase) dimer, 123 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM HEPES, 500 mM NaCl, 5 mM MgCl2, 1 mM β-mercaptoethanol, 2 mM coenzyme A (CoA), pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Oct 20
Structural enzymological studies of the long chain fatty acyl-CoA synthetase FadD5 from the mce1 operon of Mycobacterium tuberculosis. Biochem Biophys Res Commun 769:151960 (2025)
Rahman MA, Dalwani S, Venkatesan R
RgGuinier 3.7 nm
Dmax 12.0 nm
VolumePorod 210 nm3

SASDX82 – N-terminal domain of relaxase from Bacillus subtilis conjugative plasmid pLS20

UniProt ID: E9RJ23 (1-232) Relaxase
Relaxase experimental SAS data
PHENIX model
Sample: Relaxase monomer, 29 kDa Bacillus subtilis subsp. … protein
Buffer: 20 mM Tris, 300 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BL11 - NCD, ALBA on 2019 Dec 3
Activation and dimerization of the relaxase from the Bacillus subtilis conjugative plasmid pLS20 by DNA-induced cross-over of the catalytic residue
Isidro Crespo
RgGuinier 2.3 nm
Dmax 7.5 nm
VolumePorod 48 nm3

SASDX92 – N-terminal domain of relaxase from Bacillus subtilis conjugative plasmid pLS20 in complex with the core region

UniProt ID: E9RJ23 (1-232) Relaxase

UniProt ID: None (None-None) core region, single stranded
Relaxasecore region, single stranded experimental SAS data
PHENIX model
Sample: Relaxase dimer, 57 kDa Bacillus subtilis subsp. … protein
Core region, single stranded dimer, 12 kDa Bacillus subtilis DNA
Buffer: 20 mM Tris, 300 mM NaCl, 1 mM DTT, pH: 8
Experiment: SAXS data collected at BL11 - NCD, ALBA on 2019 Dec 3
Activation and dimerization of the relaxase from the Bacillus subtilis conjugative plasmid pLS20 by DNA-induced cross-over of the catalytic residue
Isidro Crespo
RgGuinier 2.5 nm
Dmax 8.2 nm
VolumePorod 50 nm3

SASDXB2 – Phosphoglycerate kinase

UniProt ID: A0A0W0EGC5 (1-416) Phosphoglycerate kinase
Phosphoglycerate kinase experimental SAS data
ALPHAFOLD model
Sample: Phosphoglycerate kinase monomer, 45 kDa Nakaseomyces glabratus protein
Buffer: 50 mM sodium phosphate, 500 mM NaCl, 500 mM imidazole, 1 mM phenylmethylsulfonyl fluoride (PMSF), pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2025 Feb 13
Integrative Structural Characterization of Candida glabrata Phosphoglycerate Kinase by Small-Angle X-ray Scattering and AlphaFold: Implications for Therapeutic Targeting in Candidiasis ACS Omega (2026)
Cuéllar-Cruz M, Maqueda Cabrera E, Siliqi D, Moreno A
RgGuinier 2.9 nm
Dmax 10.3 nm
VolumePorod 79 nm3

SASDXC2 – EGFR kinase domain duplication mutant (KDD) at 1.6 mg/ml

UniProt ID: Q504U8 (651-993) Receptor protein-tyrosine kinase (duplication mutant)
Receptor protein-tyrosine kinase (duplication mutant) experimental SAS data
DAMMIF model
Sample: Receptor protein-tyrosine kinase (duplication mutant) monomer, 80 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 250 mM NaCl, 250 mM KCl, pH: 8
Experiment: SAXS data collected at Rigaku MicroMax-007HF, Yale University on 2022 Mar 22
The role of kinase domain dimerization in EGFR activation
Zaritza Petrova
RgGuinier 3.9 nm
Dmax 13.0 nm
VolumePorod 135 nm3

SASDXF2 – Probable conserved Mce associated membrane protein (Mam1Adelta106) from M.tuberculosis

UniProt ID: O07419 (107-213) Probable conserved Mce associated membrane protein
Probable conserved Mce associated membrane protein experimental SAS data
ALPHAFOLD model
Sample: Probable conserved Mce associated membrane protein tetramer, 59 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50mM Tris, 500mM NaCl, pH: 8.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2019 Dec 10
Insight into the structure and interactions of the M. tuberculosis Mce-associated membrane proteins Mam1A-1D (2025)
Hynönen M, Perumal P, Hynönen N, Doutch J, Ma K, Venkatesan R
RgGuinier 3.2 nm
Dmax 9.0 nm
VolumePorod 177 nm3

SASDXG2 – Probable conserved Mce associated membrane protein (Mam1Adelta106) from M.tuberculosis (SANS)

UniProt ID: O07419 (107-213) Probable conserved Mce associated membrane protein
Probable conserved Mce associated membrane protein experimental SAS data
ALPHAFOLD model
Sample: Probable conserved Mce associated membrane protein tetramer, 59 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 50 mM Tris, 500 mM NaCl, D-C12E9, pH: 8.5
Experiment: SANS data collected at SANS2D, ISIS Neutron and Muon Source on 2019 Dec 10
Insight into the structure and interactions of the M. tuberculosis Mce-associated membrane proteins Mam1A-1D (2025)
Hynönen M, Perumal P, Hynönen N, Doutch J, Ma K, Venkatesan R
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 70 nm3

SASDXH2 – Mammalian translation elongation factor eEF1A2

UniProt ID: Q05639 (1-463) Mammalian translation elongation factor eEF1A2
Mammalian translation elongation factor eEF1A2 experimental SAS data
CHIMERA model
Sample: Mammalian translation elongation factor eEF1A2 monomer, 50 kDa protein
Buffer: 25 mM Tris HCl, 150 mM NaCl, 6 mM βME, 20% glycerol, 0.01mM GDP,, pH: 7.5
Experiment: SAXS data collected at Bruker Nanostar w Excillum source, Department of Chemistry, iNANO building, Aarhus Uinversity on 2023 Mar 21
Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs Nucleic Acids Research 53(21) (2025)
Novosylna O, Shalak V, Dąbrowska K, Patmanidis I, Lozhko D, Bondarchuk T, Schiøtt B, Pedersen J, Knudsen C, Nissen P, Dadlez M, Negrutskii B
RgGuinier 2.6 nm
Dmax 97.1 nm
VolumePorod 60 nm3