Browse by MODEL: Hybrid

SASDV25 – ST9a RNA, PKmutant (59 nucleotides in 0 mM MgCl2; monomer)

ST9 PKmutant (59 nt RNA) experimental SAS data
PYMOL model
Sample: ST9 PKmutant (59 nt RNA) monomer, 19 kDa RNA
Buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 1 mM DTT, 0.0002% w/v NaN3, pH:
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2024 Jan 30
A conserved viral RNA fold enables nuclease resistance across kingdoms of life. Nucleic Acids Res 53(16) (2025)
Gezelle JG, Korn SM, McDonald JT, Gong Z, Erickson A, Huang CH, Yang F, Cronin M, Kuo YW, Wimberly BT, Steckelberg AL
RgGuinier 2.5 nm
Dmax 8.8 nm
VolumePorod 29 nm3

SASDWM2 – Wild-type E3 ubiquitin-protein ligase PRT1 (Proteolysis1)

E3 ubiquitin-protein ligase PRT1 experimental SAS data
DAMMIF model
Sample: E3 ubiquitin-protein ligase PRT1 monomer, 46 kDa Arabidopsis thaliana protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 1 mM TCEP, 2% w/v glycerol, pH: 7.5
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2018 May 22
Structural basis for the recognition and ubiquitylation of type-2 N-degron substrate by PRT1 plant N-recognin Nature Communications 16(1) (2025)
Yang W, Kim S, Kim M, Shin H, Lee J, Sandmann A, Park O, Dissmeyer N, Song H
RgGuinier 3.4 nm
Dmax 12.7 nm
VolumePorod 61 nm3

SASDWL2 – C-terminal mini-Collagen VI heterotrimer

Collagen alpha-1(VI) chainCollagen alpha-2(VI) chain (R680H, K966N, Q967E)Collagen alpha-3(VI) chain (D2357R, K2367R, D2431V, R2441T, R2609A, R2610A) experimental SAS data
ALPHAFOLD model
Sample: Collagen alpha-1(VI) chain, 52 kDa Homo sapiens protein
Collagen alpha-2(VI) chain (R680H, K966N, Q967E), 53 kDa Homo sapiens protein
Collagen alpha-3(VI) chain (D2357R, K2367R, D2431V, R2441T, R2609A, R2610A), 54 kDa Homo sapiens protein
Buffer: Tris-buffered saline, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Jul 27
Collagen VI microfibril structure reveals mechanism for molecular assembly and clustering of inherited pathogenic mutations. Nat Commun 16(1):7549 (2025)
Godwin ARF, Becker MH, Dajani R, Snee M, Roseman AM, Baldock C
RgGuinier 4.8 nm
Dmax 18.7 nm
VolumePorod 478 nm3

SASDWB7 – Dynamin central region family protein from Leishmania donovani DLP1 G354D / R357S

Dynamin central region family protein experimental SAS data
BILBOMD model
Sample: Dynamin central region family protein dimer, 165 kDa Leishmania donovani protein
Buffer: 20 mM HEPES, 200 mM NaCl, 3% glycerol, pH: 7.4
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Apr 4
Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein. Mol Biochem Parasitol 263:111691 (2025)
Wuyts E, Sundaramoorthy R, Tulloch L, Monsieurs P, Eadsforth TC, Pintelon I, Timmermans JP, Dujardin JC, Domagalska MA, Caljon G, De Rycker M, Postis VLG, Wyllie S, Sterckx YG
RgGuinier 6.6 nm
Dmax 25.0 nm
VolumePorod 340 nm3

SASDXF5 – Chaperone protein DnaK (E.coli) & recombinant Heme ligase (HDP) (P.fulciparum) protein complex

Chaperone protein DnaKHeme ligase experimental SAS data
GASBOR model
Sample: Chaperone protein DnaK, 69 kDa Escherichia coli (strain … protein
Heme ligase, 28 kDa Plasmodium falciparum (isolate … protein
Buffer: 20 mM Tris-Cl, 200 mM NaCl, pH: 8
Experiment: SAXS data collected at Anton Paar SAXSpace, Chemistry Division, Bhabha Atomic Research Centre on 2019 Feb 26
Recombinant expression and purification of Plasmodium heme detoxification protein in E. coli: Challenges and discoveries. Protein Expr Purif 236:106789 (2025)
Singh R, Makde RD
RgGuinier 3.8 nm
Dmax 13.8 nm
VolumePorod 83 nm3

SASDW23 – SEC-SAXS of Trypanosoma cruzi Prolyl Oligopepetidase (TcPOP)

Prolyl endopeptidase experimental SAS data
ALPHAFOLD model
Sample: Prolyl endopeptidase monomer, 78 kDa Trypanosoma cruzi protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Apr 24
Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP. Nat Commun 16(1):7164 (2025)
Batra S, Olmo F, Ragan TJ, Kaplan M, Calvaresi V, Frank AM, Lancey C, Assadipapari M, Ying C, Struwe WB, Hesketh EL, Kelly JM, Barfod L, Campeotto I
RgGuinier 3.0 nm
Dmax 0.0 nm
VolumePorod 142 nm3

SASDSR7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form without any substrates

Gramicidin S synthase 1 (W239S) experimental SAS data
BILBOMD model
Sample: Gramicidin S synthase 1 (W239S) monomer, 127 kDa Aneurinibacillus migulanus protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.1 nm
Dmax 15.0 nm
VolumePorod 187 nm3

SASDSS7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form in the presence of 4 molar excess of L-Tyrosine

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.3 nm
Dmax 15.4 nm
VolumePorod 186 nm3

SASDST7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the apo form in the presence of 4 molar excess of L-Tyrosine and ATP analog (AMPPCP)

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.2 nm
Dmax 16.0 nm
VolumePorod 186 nm3

SASDSU7 – Gramicidin Synthetase 1 (GrsA) W239S mutant in the holo form in the presence of 4 molar excess of L-Tyrosine

Gramicidin S synthase 1 (W239S) experimental SAS data
Sample: Gramicidin S synthase 1 (W239S) monomer, 126 kDa Brevibacillus brevis protein
Buffer: 20 mM Tris pH 7.5, 100 mM NaCl, 10 mM MgCl2, 2% glycerol, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2023 Mar 14
Resting state of GrsA is a combination of two constitutively inactive isoforms that manifest long-range allosteric effects in presence of aminoacid and ATP
Raktim Roy
RgGuinier 4.1 nm
Dmax 17.5 nm
VolumePorod 181 nm3