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111 hits found for Protein W

SASDU52 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, apo form

Cereblon-midi experimental SAS data
SWISSMODEL model
Sample: Cereblon-midi monomer, 37 kDa protein
Buffer: 20 mM Hepes, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Mar 1
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.7 nm
Dmax 8.6 nm
VolumePorod 61 nm3

SASDU62 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Mezigdomide

Cereblon-midimezigdomide experimental SAS data
PYMOL model
Sample: Cereblon-midi monomer, 37 kDa protein
mezigdomide monomer, 1 kDa synthetic construct
Buffer: 20 mM Hepes, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Mar 1
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.3 nm
Dmax 7.3 nm
VolumePorod 60 nm3

SASDU72 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Pomalidomide

Cereblon-midipomalidomide experimental SAS data
Cereblon-midi pomalidomide Kratky plot
Sample: Cereblon-midi monomer, 37 kDa protein
pomalidomide monomer, 0 kDa synthetic construct
Buffer: 20 mM Hepes, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Mar 1
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.3 nm
Dmax 6.9 nm
VolumePorod 63 nm3

SASDC82 – ...protein CtRoco nucleotide free

Rab family protein experimental SAS data
DAMMIN model
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Feb 16
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 5.0 nm
Dmax 18.4 nm
VolumePorod 440 nm3

SASDU82 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Iberdomide

Cereblon-midiIberdomide experimental SAS data
Cereblon-midi Iberdomide Kratky plot
Sample: Cereblon-midi monomer, 37 kDa protein
Iberdomide monomer, 0 kDa synthetic construct
Buffer: 20 mM Hepes, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Mar 1
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.4 nm
Dmax 7.7 nm
VolumePorod 68 nm3

SASDC92 – ...protein CtRoco GppNHp

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µM GppNHp, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Feb 16
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 6.2 nm
Dmax 25.3 nm
VolumePorod 354 nm3

SASDU92 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Lenalidomide

Cereblon-midiLenalidomide experimental SAS data
Cereblon-midi Lenalidomide Kratky plot
Sample: Cereblon-midi monomer, 37 kDa protein
Lenalidomide monomer, 0 kDa synthetic construct
Buffer: 20 mM Hepes, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Mar 1
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.2 nm
Dmax 6.2 nm
VolumePorod 59 nm3

SASDCA2 – ...protein CtRoco GDP

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µM GDP, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2015 Jun 17
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 5.9 nm
Dmax 22.4 nm
VolumePorod 491 nm3

SASDCB2 – ...protein CtRoc-COR nucleotide free

Rab family protein experimental SAS data
DAMMIN model
Sample: ...protein dimer, 130 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2017 Feb 1
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 3.4 nm
Dmax 10.0 nm
VolumePorod 211 nm3

SASDCC2 – ...protein CtRoc-COR GDP

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 130 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µ M GDP, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2017 Feb 1
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 3.5 nm
Dmax 10.0 nm
VolumePorod 197 nm3

SASDCD2 – ...protein CtRoc-COR GppNHp

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 130 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µM GppNHp, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2017 Feb 1
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 3.4 nm
Dmax 10.5 nm
VolumePorod 154 nm3

SASDCE2 – ...protein CtRoco L487A GDP

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µM GDP, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2015 Jun 17
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 5.9 nm
Dmax 21.8 nm
VolumePorod 469 nm3

SASDCF2 – ...protein CtRoco L487A GppNHp

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT 200µM GppNHp, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Feb 16
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 6.0 nm
Dmax 23.0 nm
VolumePorod 436 nm3

SASDCG2 – ...protein CtRoco L487A

Rab family protein experimental SAS data
Rab family protein Kratky plot
Sample: ...protein dimer, 254 kDa Chlorobaculum tepidum protein
Buffer: 20 mM HEPES 150 mM NaCl 5 mM MgCl2 5% Glycerol 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Feb 16
...protein LRRK2 undergoes a monomer-dimer transition during GTP turnover. Nat Commun 8(1):1008 (2017)
Deyaert E, Wauters L, Guaitoli G, Konijnenberg A, Leemans M, Terheyden S, Petrovic A, Gallardo R, Nederveen-Schippers LM, Athanasopoulos PS, Pots H, Van Haastert PJM, Sobott F, Gloeckner CJ, Efremov R...
RgGuinier 5.0 nm
Dmax 18.4 nm
VolumePorod 447 nm3

SASDJ43 – ...protein-thioesterase domain from Men2

Menisporopsin singlet acyl carrier protein-thioesterase experimental SAS data
Acyl carrier protein-thioesterase domain from Men2 Rg histogram
Sample: ...protein-thioesterase monomer, 45 kDa Menisporopsin theobromae BCC … protein
Buffer: 25 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 25
...protein–thioesterase domains from a fungal nonreducing polyketide synthase FEBS Letters (2020)
...W, Winter A, Lazarus C, Crump M, Race P, Wattana‐Amorn P
RgGuinier 3.6 nm
Dmax 14.4 nm
VolumePorod 75 nm3

SASDJ53 – ...protein-thioesterase domain from Men2

Menisporopsin doublet Acyl Carrier Protein-Thioesterase experimental SAS data
Doublet acyl carrier protein-thioesterase domain from Men2 Rg histogram
Sample: ...Protein-Thioesterase monomer, 58 kDa Menisporopsis theobromae BCC … protein
Buffer: 25 mM Tris, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at B21, Diamond Light Source on 2020 Jan 25
...protein–thioesterase domains from a fungal nonreducing polyketide synthase FEBS Letters (2020)
...W, Winter A, Lazarus C, Crump M, Race P, Wattana‐Amorn P
RgGuinier 4.2 nm
Dmax 17.3 nm
VolumePorod 84 nm3

SASDXG3 – ...protein from the marine diatom Thalassiosira pseudonana

CP12 domain-containing protein experimental SAS data
GASBOR model
Sample: ...protein dimer, 34 kDa Thalassiosira pseudonana protein
Buffer: 30 mM Tris, 50 mM NaCl, 2 mM EDTA, 1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2019 Feb 23
...w type of flexible CP12 protein in the marine diatom Thalassiosira pseudonana Cell Communication and Signaling 19(1) (2021)
...W, Avilan L, Receveur-Bréchot V, Puppo C, Puppo R, Lebrun R, Gontero B, Launay H
RgGuinier 3.8 nm
Dmax 13.5 nm

SASDUQ3 – ...W protein (CTDw) of Hendra Virus (HeV)

Protein W experimental SAS data
C-terminal domain of the W protein (CTDw) of Hendra Virus (HeV) Rg histogram
Sample: Protein W monomer, 6 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2023 Apr 16
...W proteins conformational and fibrillation properties: contribution of their N- and C-terminal constituent domains. FEBS J (2024)
Pesce G, Gondelaud F, Ptchelkine D, Bignon C, Fourquet P, Longhi S
RgGuinier 2.1 nm
Dmax 7.4 nm
VolumePorod 8 nm3

SASDUR3 – ...W protein (CTDw) of Nipah Virus (NiV)

Protein W experimental SAS data
C-terminal domain of the W protein (CTDw) of Nipah Virus (NiV) Rg histogram
Sample: Protein W monomer, 6 kDa Henipavirus nipahense protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2023 Apr 16
...W proteins conformational and fibrillation properties: contribution of their N- and C-terminal constituent domains. FEBS J (2024)
Pesce G, Gondelaud F, Ptchelkine D, Bignon C, Fourquet P, Longhi S
RgGuinier 2.1 nm
Dmax 7.8 nm
VolumePorod 8 nm3

SASDJV3 – ...Protein (GAP) domain (73-204) of Vibrio cholerae Outer Protein E (VopE)

Outer membrane virulence protein yopE experimental SAS data
Outer membrane virulence protein yopE Kratky plot
Sample: ...protein yopE monomer, 15 kDa Vibrio cholerae protein
Buffer: 10 mM HEPES-HCl, pH 7.4, 150 mM NaCl, 0.5 mM TCEP, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Jun 29
...protein ( GAP ) VopE by an integrated NMR / SAXS approach Protein Science (2022)
...W, Tonelli M, Lee Y, Light S, Cornilescu G, Chakravarthy S
RgGuinier 2.0 nm
Dmax 8.0 nm
VolumePorod 28 nm3

SASDF34 – Free Nuclear receptor CoRepressor NID (spanning from residue Gln2059 to Glu2325)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) experimental SAS data
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2016 Jun 20
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 4.7 nm
Dmax 17.7 nm
VolumePorod 102 nm3

SASDF44 – RXR/RAR Heterodimer : N-CoRNID Complex (1:1)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID)Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD)Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) experimental SAS data
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) Kratky plot
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2014 Jul 23
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 4.8 nm
Dmax 19.4 nm
VolumePorod 167 nm3

SASDF54 – RXRΔH12/RAR Heterodimer : N-CoRNID Complex (1:1)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID)Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD)Retinoid-X receptor alpha (RXR-alpha) Δ helix12 experimental SAS data
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) Retinoid-X receptor alpha (RXR-alpha) Δ helix12 Kratky plot
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Δ helix12 monomer, 24 kDa Mus musculus protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2014 Jul 23
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 4.2 nm
Dmax 15.7 nm
VolumePorod 183 nm3

SASDF64 – ...with RAR inverse agonist (BMS493)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID)Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD)Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) experimental SAS data
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) Kratky plot
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2014 Jul 23
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 4.8 nm
Dmax 19.5 nm
VolumePorod 178 nm3

SASDF74 – RXR/RARI396E Heterodimer : N-CoRNID Complex (1:1)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID)Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD)Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) mutant I396E experimental SAS data
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) mutant I396E Kratky plot
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) mutant I396E monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2015 Mar 9
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 5.3 nm
Dmax 22.4 nm
VolumePorod 171 nm3

SASDF84 – ...with RAR agonist (Am580)

Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID)Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD)Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) experimental SAS data
Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) Kratky plot
Sample: Nuclear receptor CoRepressor 1; Nuclear Receptor Interaction Domain (NID) monomer, 29 kDa Mus musculus protein
Retinoid-X receptor alpha (RXR-alpha) Ligand Binding Domain (LBD) monomer, 26 kDa Mus musculus protein
Retinoic acid receptor alpha (RAR-alpha) Ligand binding domain (LDB) monomer, 28 kDa Homo sapiens protein
Buffer: 50 mM Tris-HCl, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2014 Jul 23
...Protein Disorder in Retinoic Acid Receptor Heterodimer and Its Corepressor Regulates Gene Expression. Structure (2019)
...W, le Maire A, Bernadó P
RgGuinier 4.2 nm
Dmax 17.2 nm
VolumePorod 131 nm3

SASDG95 – ...protein complex

Resistance to inhibitors of cholinesterase 8 homolog AGuanine nucleotide-binding protein G(i) subunit alpha-1 experimental SAS data
DAMMIF model
Sample: Resistance to inhibitors of cholinesterase 8 homolog A monomer, 56 kDa Rattus norvegicus protein
...protein G(i) subunit alpha-1 monomer, 38 kDa Rattus norvegicus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 30
...protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1 Nature Communications 11(1) (2020)
...Wohlkonig A, Tall G, Steyaert J, Chiu W, Sprang S
RgGuinier 3.5 nm
Dmax 11.5 nm
VolumePorod 120 nm3

SASDQB5 – Elongation factor Tu from Mycobacterium tuberculosis

Elongation factor Tu experimental SAS data
DAMMIN model
Sample: Elongation factor Tu monomer, 44 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jul 12
...protein translation of Mycobacterium tuberculosis. Commun Biol 5(1):1052 (2022)
...W, Li Y, Li Z, Qi Q, Lan X, Shen H, Gan J, Zhao G, Li J
RgGuinier 3.5 nm
Dmax 9.0 nm
VolumePorod 94 nm3

SASDQC5 – Elongation factor Ts from Mycobacterium tuberculosis

Elongation factor Ts experimental SAS data
DAMMIN model
Sample: Elongation factor Ts monomer, 29 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jul 12
...protein translation of Mycobacterium tuberculosis. Commun Biol 5(1):1052 (2022)
...W, Li Y, Li Z, Qi Q, Lan X, Shen H, Gan J, Zhao G, Li J
RgGuinier 2.7 nm
Dmax 10.1 nm
VolumePorod 46 nm3

SASDFD5 – Tetracycline repressor (class D), TetR(D)

Tetracycline repressor (class D) experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Tetracycline repressor (class D) dimer, 47 kDa Escherichia coli protein
Buffer: 50 mM Tris/HCl 150 mM NaCl 10 mM MgCl2, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Sep 23
Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. ...Proteins Proteom :140404 (2020)
...Werten S, Girbardt B, Berndt L, Delcea M, Hinrichs W
RgGuinier 2.6 nm
Dmax 7.7 nm
VolumePorod 85 nm3

SASDQD5 – Elongation factor-Tu and Elongation factor-Ts complex from Mycobacterium tuberculosis

Elongation factor TuElongation factor Ts experimental SAS data
DAMMIN model
Sample: Elongation factor Tu monomer, 44 kDa Mycobacterium tuberculosis (strain … protein
Elongation factor Ts monomer, 29 kDa Mycobacterium tuberculosis (strain … protein
Buffer: 20 mM Tris, 100 mM NaCl, pH: 8
Experiment: SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2021 Jul 12
...protein translation of Mycobacterium tuberculosis. Commun Biol 5(1):1052 (2022)
...W, Li Y, Li Z, Qi Q, Lan X, Shen H, Gan J, Zhao G, Li J
RgGuinier 3.1 nm
Dmax 11.2 nm
VolumePorod 111 nm3

SASDFE5 – ...with 5a,6-anhydrotetracycline (ATc)

Tetracycline repressor (class D)5a,6-anhydrotetracycline experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Tetracycline repressor (class D) dimer, 47 kDa Escherichia coli protein
5a,6-anhydrotetracycline dimer, 1 kDa
Buffer: 50 mM Tris/HCl 150 mM NaCl 10 mM MgCl2, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Sep 23
Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding. ...Proteins Proteom :140404 (2020)
...Werten S, Girbardt B, Berndt L, Delcea M, Hinrichs W
RgGuinier 2.6 nm
Dmax 6.8 nm
VolumePorod 77 nm3

SASDAN5 – Cross-linked complex CytC_Adr

Cytochrome CAdrenodoxin experimental SAS data
DAMMIN model
Sample: Cytochrome C monomer, 11 kDa Escherichia coli protein
Adrenodoxin monomer, 11 kDa Escherichia coli protein
Buffer: 20 mM HEPES 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2006 Jun 15
...wo proteins studied by solution scattering and paramagnetic NMR spectroscopy. J Am Chem Soc 130(20):6395-403 (2008)
...W, Hannemann F, Konarev PV, Svergun DI, Bernhardt R, Ubbink M
RgGuinier 2.1 nm
Dmax 8.5 nm
VolumePorod 42 nm3

SASDAP5 – Native complex CytC_Adr

Cytochrome C dimerAdrenodoxin dimer experimental SAS data
DAMMIN model
Sample: Cytochrome C dimer dimer, 22 kDa Escherichia coli protein
Adrenodoxin dimer dimer, 22 kDa Escherichia coli protein
Buffer: 20 mM HEPES 2 mM DTT, pH: 7.4
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2006 Jun 15
...wo proteins studied by solution scattering and paramagnetic NMR spectroscopy. J Am Chem Soc 130(20):6395-403 (2008)
...W, Hannemann F, Konarev PV, Svergun DI, Bernhardt R, Ubbink M
RgGuinier 2.9 nm
Dmax 9.5 nm
VolumePorod 64 nm3

SASDHY5 – ...protein crystals recombinantly expressed within High Five insect cells

Photinus pyralis firefly luciferase experimental SAS data
Photinus pyralis firefly luciferase Kratky plot
Sample: Photinus pyralis firefly luciferase , 61 kDa Photinus pyralis protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDJY5 – ...protein crystals recombinantly expressed within High Five insect cells

Inosine-5'-monophosphate dehydrogenase experimental SAS data
Inosine-5'-monophosphate dehydrogenase Kratky plot
Sample: Inosine-5'-monophosphate dehydrogenase , 59 kDa Trypanosoma brucei brucei protein
Buffer: 20 mM Tris, 150 mM NaCl,, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDHZ5 – ...protein crystals recombinantly expressed within High Five insect cells

Inosine-5'-monophosphate dehydrogenase experimental SAS data
Inosine-5'-monophosphate dehydrogenase Kratky plot
Sample: Inosine-5'-monophosphate dehydrogenase , 59 kDa Trypanosoma brucei brucei protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDJZ5 – ...protein crystals recombinantly expressed within Sf9 insect cells

Inosine-5'-monophosphate dehydrogenase experimental SAS data
Inosine-5'-monophosphate dehydrogenase Kratky plot
Sample: Inosine-5'-monophosphate dehydrogenase , 59 kDa Trypanosoma brucei brucei protein
Buffer: 20 mM Tris, 150 mM NaCl,, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH26 – ...protein crystals recombinantly expressed within High Five insect cells

Cathepsin B-like cysteine protease experimental SAS data
Cathepsin B-like cysteine protease Kratky plot
Sample: Cathepsin B-like cysteine protease , 37 kDa Trypanosoma brucei protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH36 – ...Woronin body major protein (HEX-1) crystals recombinantly expressed within High Five insect cells

Woronin body major protein experimental SAS data
Woronin body major protein Kratky plot
Sample: Woronin body major protein , 19 kDa Neurospora crassa protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH46 – ...with mock recombinant baculovirus (rBV)

mock recombinant baculovirus experimental SAS data
mock recombinant baculovirus Kratky plot
Sample: mock recombinant baculovirus , 0 kDa unidentified baculovirus
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH56 – High Five insect cell culture (control; uninfected)

High Five insect cells experimental SAS data
High Five insect cells Kratky plot
Sample: High Five insect cells , 0 kDa Trichoplusia ni
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH66 – ...Woronin body major protein (HEX-1) crystals recombinantly expressed within High Five insect cells (cell-culture serial dilution series)

Woronin body major protein experimental SAS data
Woronin body major protein Kratky plot
Sample: Woronin body major protein , 19 kDa Neurospora crassa protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH76 – ...protein crystals recombinantly expressed within High Five insect cells (cell-culture serial dilution series)

Cathepsin B-like cysteine protease experimental SAS data
Cathepsin B-like cysteine protease Kratky plot
Sample: Cathepsin B-like cysteine protease , 37 kDa Trypanosoma brucei protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2019 Dec 3
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH86 – ...protein crystals recombinantly expressed within High Five insect cells

Cathepsin B-like cysteine protease experimental SAS data
Cathepsin B-like cysteine protease Kratky plot
Sample: Cathepsin B-like cysteine protease , 37 kDa Trypanosoma brucei protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDH96 – ...protein crystals recombinantly expressed within Sf9 insect cells

Cathepsin B-like cysteine protease experimental SAS data
Cathepsin B-like cysteine protease Kratky plot
Sample: Cathepsin B-like cysteine protease , 37 kDa Trypanosoma brucei protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDHA6 – ...Woronin body major protein (HEX-1) crystals recombinantly expressed within High Five insect cells

Woronin body major protein experimental SAS data
Woronin body major protein Kratky plot
Sample: Woronin body major protein , 19 kDa Neurospora crassa protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDHB6 – ...Woronin body major protein (HEX-1) crystals recombinantly expressed within Sf9 insect cells

Woronin body major protein experimental SAS data
Woronin body major protein Kratky plot
Sample: Woronin body major protein , 19 kDa Neurospora crassa protein
Buffer: TBS (20 mM Tris, 150 mM NaCl),, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Nov 21
...wn protein crystals via a small-angle X-ray scattering/X-ray powder diffraction synergistic approach Journal of Applied Crystallography 53(5) (2020)
...W, Triandafillidis D, Valmas A, Margiolaki I, Svergun D, Redecke L

SASDSF6 – ...W)

Ubiquilin-2 (∆1-449)-W experimental SAS data
Ubiquilin-2 (∆1-449)-W Kratky plot
Sample: ...W dimer, 35 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 0.5 mM EDTA, 0.02 % NaN3, pH: 6.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2022 Feb 16
UBQLN2 domain deletion constructs
Sarasi Galagedera
RgGuinier 3.8 nm
Dmax 18.5 nm
VolumePorod 50 nm3

SASDNK6 – ...protein at 1 mg/ml

Retinoblastoma-associated protein experimental SAS data
Retinoblastoma-associated protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 2.4 nm
Dmax 7.4 nm
VolumePorod 66 nm3

SASDNL6 – ...protein at 2 mg/ml

Retinoblastoma-associated protein experimental SAS data
Retinoblastoma-associated protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 2.5 nm
Dmax 7.9 nm
VolumePorod 64 nm3

SASDNM6 – ...protein at 4 mg/ml

Retinoblastoma-associated protein experimental SAS data
Retinoblastoma-associated protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 2.6 nm
Dmax 10.0 nm
VolumePorod 68 nm3

SASDNN6 – ...protein at 4.2 mg/ml

Early E1A protein experimental SAS data
Early E1A protein Kratky plot
Sample: ...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at ...WING, SOLEIL on 2019 Mar 24
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 4.0 nm

SASDVN6 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Boc-VcN

Cereblon-midi experimental SAS data
Cereblon-midi Kratky plot
Sample: Cereblon-midi monomer, 37 kDa synthetic construct protein
Buffer: 20 mM HEPES, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 29
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.3 nm
Dmax 9.1 nm
VolumePorod 63 nm3

SASDNP6 – ...protein at 5.6 mg/ml

Early E1A protein experimental SAS data
Early E1A protein Kratky plot
Sample: ...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at ...WING, SOLEIL on 2019 Mar 24
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 4.2 nm

SASDVP6 – Cereblon-midi (CRBNmidi), an engineered Cereblon construct for crystallographic and biophysical studies, bound to Boc-AcQ

Cereblon-midi experimental SAS data
Cereblon-midi Kratky plot
Sample: Cereblon-midi monomer, 37 kDa synthetic construct protein
Buffer: 20 mM HEPES, 500 mM NaCl, 0.5 mM TCEP, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jun 29
...protein degraders Nature Communications 15(1) (2024)
...Wijaya A, Rodriguez-Rios M, Sturbaut M, Lynch D, Farnaby W, Nakasone M, Zollman D, Ciulli A
RgGuinier 2.4 nm
Dmax 9.6 nm
VolumePorod 62 nm3

SASDNQ6 – ...protein at 7.0 mg/ml

Early E1A protein experimental SAS data
Early E1A protein Kratky plot
Sample: ...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at ...WING, SOLEIL on 2019 Mar 24
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 4.1 nm

SASDNR6 – ...protein/Early E1A protein (RB-E1A) complex at 0.7 mg/ml

Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 2.9 nm
Dmax 10.0 nm
VolumePorod 80 nm3

SASDNS6 – ...protein/Early E1A protein (RB-E1A) complex at 1.4 mg/ml

Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 84 nm3

SASDNT6 – ...protein/Early E1A protein (RB-E1A) complex at 2.7 mg/ml

Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 3.3 nm
Dmax 17.0 nm
VolumePorod 93 nm3

SASDNU6 – ...protein/Early E1A protein (RB-E1A) complex - merged data from concentration series measurements

Retinoblastoma-associated proteinEarly E1A protein experimental SAS data
Retinoblastoma-associated protein Early E1A protein Kratky plot
Sample: ...protein monomer, 41 kDa Homo sapiens protein
...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Jul 14
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 3.0 nm
Dmax 12.0 nm
VolumePorod 84 nm3

SASDNV6 – ...protein, SEC-SAXS data

Early E1A protein experimental SAS data
Early E1A protein Kratky plot
Sample: ...protein monomer, 13 kDa Human adenovirus C … protein
Buffer: 20 mM sodium phosphate pH 7.0, 200 mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at ...WING, SOLEIL on 2019 Mar 24
...protein regions. Nat Struct Mol Biol (2022)
González-Foutel NS, Glavina J, Borcherds WM, Safranchik M, Barrera-Vilarmau S, Sagar A, Estaña A, Barozet A, Garrone NA, Fernandez-Ballester G, Blanes-Mira C, Sánchez IE, de Prat-Gay G, Cortés J, Bern...
RgGuinier 3.6 nm
Dmax 17.5 nm
VolumePorod 45 nm3

SASDF27 – Brain and Muscle ARNT-Like 1 from Mus musculus (D530-L625), monomer, trans-conformation locking mutation P624A

Aryl hydrocarbon receptor nuclear translocator-like protein 1 experimental SAS data
DAMMIN model
Sample: ...protein 1 monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 2.8 nm
Dmax 11.0 nm

SASDF37 – ...protein (Mus musculus), mutation L664C

Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C experimental SAS data
DAMMIN model
Sample: ...protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 1.9 nm
Dmax 8.1 nm

...W37 – ...with Four Functional Domains (2x SpyCatcher, RFP, DCV)

TET12-2Sc-RFP-DCV experimental SAS data
MODELLER model
Sample: TET12-2Sc-RFP-DCV monomer, 109 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Sep 24
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 4.4 nm
Dmax 13.6 nm
VolumePorod 300 nm3

SASDF47 – ...with BMAL1 (D530-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

Aryl hydrocarbon receptor nuclear translocator-like protein 1Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C experimental SAS data
DAMMIN model
Sample: ...protein 1 monomer, 10 kDa Mus musculus protein
...protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 2.8 nm
Dmax 11.5 nm

...W47 – ...with Four Functional Domains (2x SpyCatcher, RFP, DCV) and Dual SpyCatcher-SpyTag Linkages with DCV-RFP-St Extension

TET12-2Sc-RFP-DCVDCV-RFP-StDCV-RFP-St experimental SAS data
SREFLEX model
Sample: TET12-2Sc-RFP-DCV monomer, 109 kDa synthetic construct protein
DCV-RFP-St monomer, 41 kDa synthetic construct protein
DCV-RFP-St monomer, 41 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Sep 24
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 5.1 nm
Dmax 15.4 nm
VolumePorod 480 nm3

SASDF57 – ...with BMAL1 (G517-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD)Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP) experimental SAS data
DAMMIN model
Sample: Brain and muscle ARNT-like 1 (G517-L625) including transactivation domain (TAD) monomer, 11 kDa Mus musculus protein
...protein (CBP) monomer, 10 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 3.1 nm
Dmax 13.7 nm

...W57 – ...with Four Functional Domains (2x SpyCatcher, RFP, DCV) and Dual SpyCatcher-SpyTag Linkages with DCV-GFP-St Extension

TET12-2Sc-RFP-DCVDCV-GFP-StDCV-GFP-St experimental SAS data
MODELLER model
Sample: TET12-2Sc-RFP-DCV monomer, 109 kDa synthetic construct protein
DCV-GFP-St monomer, 41 kDa synthetic construct protein
DCV-GFP-St monomer, 41 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Mar 18
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 5.8 nm
Dmax 17.3 nm
VolumePorod 580 nm3

SASDF67 – ...with BMAL1 (G490-L625) including C-terminal transactivation domain (TAD) (Mus musculus)

Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP)Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD) experimental SAS data
DAMMIN model
Sample: ...protein (CBP) monomer, 10 kDa Mus musculus protein
Brain and muscle ARNT-like 1 (G490-L625) including transactivation domain (TAD) monomer, 14 kDa Mus musculus protein
Buffer: 25 mM Hepes, 150 NaCl, 1 mM DTT, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 3.8 nm
Dmax 17.5 nm

...W67 – ...protein consisting of DCV, RFP and SpyTag domain

DCV-RFP-St experimental SAS data
MODELLER model
Sample: DCV-RFP-St monomer, 41 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Sep 24
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 2.8 nm
Dmax 9.2 nm
VolumePorod 60 nm3

SASDF77 – ...protein tethered to 1-10

Kinase-inducible domain interacting (KIX) domain of CREB-binding protein (CBP), mutation L664C1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one experimental SAS data
DAMMIN model
Sample: ...protein (CBP), mutation L664C monomer, 10 kDa Mus musculus protein
1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one monomer, 0 kDa
Buffer: 25 mM Hepes, 150 NaCl, 5% Glycerol, pH: 7.2
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 May 27
...with the KIX domain of the CREB-binding protein. J Biol Chem (2019)
...W, Distler U, Chojnacki JE, Köhn M, Tenzer S, Sönnichsen C, Wolf E
RgGuinier 1.7 nm
Dmax 6.4 nm

...W77 – ...protein consisting of DCV, GFP and SpyTag domain

DCV-GFP-St experimental SAS data
MODELLER model
Sample: DCV-GFP-St monomer, 41 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Mar 18
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 2.8 nm
Dmax 9.1 nm
VolumePorod 54 nm3

...W87 – DGSt-LucSc - DCV-GFP-SpyTag and NanoLuc-SpyCatcher Conjugate via SpyCatcher-SpyTag Reaction

DCV-GFP-StNanoLuc-Sc experimental SAS data
SREFLEX model
Sample: DCV-GFP-St monomer, 41 kDa synthetic construct protein
NanoLuc-Sc monomer, 30 kDa synthetic construct protein
Buffer: 20 mM Tris, 150 mM NaCL, 3% glycerol, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2024 Mar 18
...Protein-DNA Composite Nanostructures: from Nanostructure Construction to Protein-Induced Micro-Scale Material Self-Assembly and Functionalization. Small 21(30):e2502060 (2025)
...W, Strmšek Ž, Snoj J, Škarabot M, Jerala R
RgGuinier 3.4 nm
Dmax 12.5 nm
VolumePorod 105 nm3

SASDQB7 – ...within the N-terminal domain of P/V/W protein of Hendra virus (PNT3 region)

Non-structural protein V experimental SAS data
Non-structural protein V Kratky plot
Sample: ...protein V monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 50 mM sodium phosphate, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2022 Jul 14
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies International Journal of Molecular Sciences 24(1):399 (2022)
Nilsson J, Baroudi H, Gondelaud F, Pesce G, Bignon C, Ptchelkine D, Chamieh J, Cottet H, Kajava A, Longhi S
RgGuinier 3.7 nm
Dmax 19.0 nm
VolumePorod 48 nm3

SASDQC7 – ...within the N-terminal domain of P/V/W protein of Hendra virus (PNT3 region) mutated YYY --> AAA

Non-structural protein V (Y211A, Y212A, Y213A mutant) experimental SAS data
Non-structural protein V (Y211A, Y212A, Y213A mutant) Kratky plot
Sample: ...protein V (Y211A, Y212A, Y213A mutant) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 50 mM sodium phosphate, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2022 Jul 14
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies International Journal of Molecular Sciences 24(1):399 (2022)
Nilsson J, Baroudi H, Gondelaud F, Pesce G, Bignon C, Ptchelkine D, Chamieh J, Cottet H, Kajava A, Longhi S
RgGuinier 4.0 nm
Dmax 19.0 nm
VolumePorod 49 nm3

SASDQD7 – ...within the N-terminal domain of P/V/W protein of Hendra virus (PNT3 region, C-terminal truncated)

Non-structural protein V experimental SAS data
Non-structural protein V Kratky plot
Sample: ...protein V monomer, 9 kDa Hendra virus (isolate … protein
Buffer: 50 mM sodium phosphate, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2022 Jul 14
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies International Journal of Molecular Sciences 24(1):399 (2022)
Nilsson J, Baroudi H, Gondelaud F, Pesce G, Bignon C, Ptchelkine D, Chamieh J, Cottet H, Kajava A, Longhi S
RgGuinier 2.8 nm
Dmax 13.0 nm
VolumePorod 22 nm3

SASDQE7 – ...within the N-terminal domain of P/V/W protein of Hendra virus (PNT3 region C-terminal truncated), mutated YYY --> AAA

Non-structural protein V (ΔC-terminal and Y111A, Y112A, Y113A mutant) experimental SAS data
Non-structural protein V (ΔC-terminal and Y111A, Y112A, Y113A mutant) Kratky plot
Sample: ...protein V (ΔC-terminal and Y111A, Y112A, Y113A mutant) monomer, 9 kDa Hendra virus (isolate … protein
Buffer: 50 mM sodium phosphate, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2022 Jul 14
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies International Journal of Molecular Sciences 24(1):399 (2022)
Nilsson J, Baroudi H, Gondelaud F, Pesce G, Bignon C, Ptchelkine D, Chamieh J, Cottet H, Kajava A, Longhi S
RgGuinier 2.7 nm
Dmax 12.5 nm
VolumePorod 21 nm3

SASDQF7 – ...within N-terminal domain of P/V/W protein of Nipah virus (PNT3 region)

Non-structural protein V experimental SAS data
Non-structural protein V Kratky plot
Sample: ...protein V monomer, 15 kDa Nipah henipavirus protein
Buffer: 50 mM sodium phosphate, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2022 Jul 14
Molecular Determinants of Fibrillation in a Viral Amyloidogenic Domain from Combined Biochemical and Biophysical Studies International Journal of Molecular Sciences 24(1):399 (2022)
Nilsson J, Baroudi H, Gondelaud F, Pesce G, Bignon C, Ptchelkine D, Chamieh J, Cottet H, Kajava A, Longhi S
RgGuinier 3.7 nm
Dmax 16.5 nm
VolumePorod 47 nm3

SASDRU7 – ...protein (Ace2-Fc) at 3.81 mg/ml

Angiotensin-converting enzyme 2 chimera with the Fc region of the immunoglobulin heavy constant gamma 4 experimental SAS data
Angiotensin-converting enzyme 2 chimera with the Fc region of the immunoglobulin heavy constant gamma 4 Kratky plot
Sample: ...with the Fc region of the immunoglobulin heavy constant gamma 4 dimer, 217 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at Rigaku BioSAXS-1000, SFB 1035, Technische Universität München on 2021 Jul 5
...proteins targeting SARS-CoV-2. Commun Biol 6(1):386 (2023)
...wicz GM, Reiter A, Sattler M, Brockmeyer C, Buchner J
RgGuinier 5.5 nm
Dmax 18.6 nm
VolumePorod 408 nm3

SASDAB8 – Protein Interacting with C-kinase 1 (PICK1) LKV, dimer contribution (data decomposition).

PRKCA-binding protein experimental SAS data
Protein Interacting with C-kinase 1 (PICK1) LKV, dimer contribution (data decomposition). Rg histogram
Sample: ...protein dimer, 93 kDa Rattus norvegicus protein
Buffer: 50 mM Tris 125 mM NaCl 0.01 vol% reduced TX-100, pH: 7.4
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2015 May 11
...Protein PICK1 Determined by Small-Angle X-Ray Scattering. Structure 23(7):1258-1270 (2015)
...W, Teilum K, Vestergaard B, Weinstein H, Gether U, Arleth L, Madsen KL
RgGuinier 6.0 nm
Dmax 20.0 nm
VolumePorod 205 nm3

SASDVC8 – ...protein P/V/W PNT3 domain

Protein W experimental SAS data
Hendra virus protein P/V/W PNT3 domain Rg histogram
Sample: Protein W monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
...Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.4 nm
Dmax 13.5 nm
VolumePorod 42 nm3

SASDAD8 – ...protein, (DpV84gp022) Deerpox virus

Antiapoptotic membrane protein experimental SAS data
Antiapoptotic membrane protein Kratky plot
Sample: ...protein dimer, 39 kDa ...W-1170-84 protein
Buffer: 25 mM HEPES 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at ...WAXS, Australian Synchrotron on 2013 May 4
Structural basis of Deerpox virus-mediated inhibition of apoptosis. Acta Crystallogr D Biol Crystallogr 71(Pt 8):1593-603 (2015)
Burton DR, Caria S, Marshall B, Barry M, Kvansakul M
RgGuinier 2.6 nm
Dmax 11.1 nm
VolumePorod 61 nm3

SASDVD8 – ...protein P/V/W PNT3 low-K domain

Protein W (artificial PNT3 variant - low-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 low-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - low-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at BM29, ESRF on 2023 Jun 13
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
...Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.8 nm
Dmax 18.0 nm
VolumePorod 48 nm3

SASDPE8 – SMARCA2 bromodomain (isoform1):Protac (ACBI1):VCB (VHL-elongin C-elongin B)

Probable global transcription activator SNF2L2 (isoform 1)von Hippel-Lindau disease tumor suppressorElongin-BElongin-CACBI1 protac experimental SAS data
Probable global transcription activator SNF2L2 (isoform 1) von Hippel-Lindau disease tumor suppressor Elongin-B Elongin-C ACBI1 protac Kratky plot
Sample: Probable global transcription activator SNF2L2 (isoform 1) monomer, 16 kDa Homo sapiens protein
von Hippel-Lindau disease tumor suppressor monomer, 19 kDa Homo sapiens protein
Elongin-B monomer, 12 kDa Homo sapiens protein
Elongin-C monomer, 11 kDa Homo sapiens protein
ACBI1 protac monomer, 1 kDa
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at ...with MetalJet, Département de Biochimie, Université de Montréal on 2021 Aug 11
...protein degradation by integrating molecular dynamics simulations with structural mass spectrometry. Nat Commun 13(1):5884 (2022)
...Wiewiora R, McDargh ZA, Pei F, Pal R, Ribeiro JV, Wilkerson T, Sachdeva V, Gao N, Jain S, Sparks S, Li Y, Vinitsky A, Zhang X, Razavi AM, Kolossváry I, Imbriglio J, Evdokimov A, Bergeron L, Zhou W, Ad...
RgGuinier 3.3 nm
Dmax 12.5 nm
VolumePorod 83 nm3

SASDVE8 – ...protein P/V/W PNT3 high-K domain

Protein W (artificial PNT3 variant - high-kappa) experimental SAS data
Hendra virus protein P/V/W PNT3 high-K domain Rg histogram
Sample: Protein W (artificial PNT3 variant - high-kappa) monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.2
Experiment: SAXS data collected at ...WING, SOLEIL on 2024 Apr 5
Unraveling the molecular grammar and the structural transitions underlying the fibrillation of a viral fibrillogenic domain. Protein Sci 34(3):e70068 (2025)
...Walimbe A, Bignon C, Ptchelkine D, Brocca S, Mukhopadyay S, Longhi S
RgGuinier 3.1 nm
Dmax 14.7 nm
VolumePorod 54 nm3

SASDPF8 – SMARCA2 bromodomain (isoform2):Protac (ACBI1):VCB (VHL-elongin C-elongin B)

von Hippel-Lindau disease tumor suppressorElongin-BElongin-CACBI1 protacProbable global transcription activator SNF2L2 (isoform 2) experimental SAS data
von Hippel-Lindau disease tumor suppressor Elongin-B Elongin-C ACBI1 protac Probable global transcription activator SNF2L2 (isoform 2) Kratky plot
Sample: von Hippel-Lindau disease tumor suppressor monomer, 19 kDa Homo sapiens protein
Elongin-B monomer, 12 kDa Homo sapiens protein
Elongin-C monomer, 11 kDa Homo sapiens protein
ACBI1 protac monomer, 1 kDa
Probable global transcription activator SNF2L2 (isoform 2) monomer, 14 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 150 mM NaCl, 1 mM DTT, pH: 7.5
Experiment: SAXS data collected at ...with MetalJet, Département de Biochimie, Université de Montréal on 2021 Aug 11
...protein degradation by integrating molecular dynamics simulations with structural mass spectrometry. Nat Commun 13(1):5884 (2022)
...Wiewiora R, McDargh ZA, Pei F, Pal R, Ribeiro JV, Wilkerson T, Sachdeva V, Gao N, Jain S, Sparks S, Li Y, Vinitsky A, Zhang X, Razavi AM, Kolossváry I, Imbriglio J, Evdokimov A, Bergeron L, Zhou W, Ad...
RgGuinier 3.2 nm
Dmax 11.1 nm
VolumePorod 75 nm3

SASDS69 – ...protein 10 (Nsp10)

Replicase polyprotein 1ab (Non-structural protein 10) experimental SAS data
Replicase polyprotein 1ab (Non-structural protein 10) Kratky plot
Sample: ...protein 1ab (Non-structural protein 10) monomer, 15 kDa Severe acute respiratory … protein
Buffer: 10 mM HEPES, 300 mM NaCl, 1.5% (v/v) glycerol, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Nov 25
...Protein 10 Stimulators Studied by Small Angle X-ray Scattering International Journal of Molecular Sciences 24(17):13649 (2023)
...W, Fisher S, Lou J, Sele C, Ma S, Rasmussen A, Pinotsis N, Kozielski F
RgGuinier 1.7 nm
Dmax 5.9 nm
VolumePorod 21 nm3

SASDS79 – ...protein 10 (Nsp10: C-terminal truncation variant)

Replicase polyprotein 1ab (Non-structural protein 10 - Δ4386-4392) experimental SAS data
Replicase polyprotein 1ab (Non-structural protein 10 - Δ4386-4392) Kratky plot
Sample: ...protein 1ab (Non-structural protein 10 - Δ4386-4392) monomer, 14 kDa Severe acute respiratory … protein
Buffer: 10 mM HEPES, 300 mM NaCl, 1.5% (v/v) glycerol, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Nov 25
...Protein 10 Stimulators Studied by Small Angle X-ray Scattering International Journal of Molecular Sciences 24(17):13649 (2023)
...W, Fisher S, Lou J, Sele C, Ma S, Rasmussen A, Pinotsis N, Kozielski F
RgGuinier 1.6 nm
Dmax 5.4 nm
VolumePorod 19 nm3

SASDS89 – ...protein 10 (Nsp10: N- and C-terminal truncation variant)

Replicase polyprotein 1ab (Non-structural protein 10 - Δ4254-4262; Δ4386-4392) experimental SAS data
Replicase polyprotein 1ab (Non-structural protein 10 - Δ4254-4262; Δ4386-4392) Kratky plot
Sample: ...protein 1ab (Non-structural protein 10 - Δ4254-4262; Δ4386-4392) monomer, 13 kDa Severe acute respiratory … protein
Buffer: 10 mM HEPES, 300 mM NaCl, 1.5% (v/v) glycerol, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2022 Nov 25
...Protein 10 Stimulators Studied by Small Angle X-ray Scattering International Journal of Molecular Sciences 24(17):13649 (2023)
...W, Fisher S, Lou J, Sele C, Ma S, Rasmussen A, Pinotsis N, Kozielski F
RgGuinier 1.5 nm
Dmax 5.1 nm
VolumePorod 16 nm3

SASDC99 – ...protein Particle (NLP) from In Vitro Assembly - 100% D2O SANS

Apolipoprotein A-I1,2-dimyristoyl-sn-glycero-3-phosphocholine experimental SAS data
Apolipoprotein A-I 1,2-dimyristoyl-sn-glycero-3-phosphocholine Kratky plot
Sample: ...protein A-I dimer, 50 kDa Mus musculus protein
1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
Buffer: PBS in D2O, pH: 7.4
Experiment: SANS data collected at NG7, NIST Center for High Resolution Neutron Scattering (CHRNS) on 2015 Nov 25
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 3.1 nm
Dmax 9.1 nm

SASDS99 – ...protein 10 (Nsp10)

Replicase polyprotein 1ab (Non-structural protein 10) experimental SAS data
Replicase polyprotein 1ab (Non-structural protein 10) Kratky plot
Sample: ...protein 1ab (Non-structural protein 10) monomer, 16 kDa Severe acute respiratory … protein
Buffer: 10 mM HEPES, 300 mM NaCl, 1.5% (v/v) glycerol, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Feb 6
...Protein 10 Stimulators Studied by Small Angle X-ray Scattering International Journal of Molecular Sciences 24(17):13649 (2023)
...W, Fisher S, Lou J, Sele C, Ma S, Rasmussen A, Pinotsis N, Kozielski F
RgGuinier 1.7 nm
Dmax 5.9 nm
VolumePorod 19 nm3

SASDCA9 – ...protein Particle (NLP) from In Vitro Assembly - SAXS

Apolipoprotein A-I1,2-dimyristoyl-sn-glycero-3-phosphocholine experimental SAS data
Apolipoprotein A-I 1,2-dimyristoyl-sn-glycero-3-phosphocholine Kratky plot
Sample: ...protein A-I dimer, 50 kDa Mus musculus protein
1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
Buffer: PBS in D2O, pH: 7.4
Experiment: SAXS data collected at SAXSLab Bio-Ganesha, Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology (IBBR/NIST) on 2015 Nov 24
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 4.8 nm
Dmax 12.0 nm

SASDSA9 – ...protein 10 (Nsp10)

Replicase polyprotein 1ab (Non-structural protein 10) experimental SAS data
Replicase polyprotein 1ab (Non-structural protein 10) Kratky plot
Sample: ...protein 1ab (Non-structural protein 10) monomer, 15 kDa Middle East respiratory … protein
Buffer: 10 mM HEPES, 300 mM NaCl, 1.5% (v/v) glycerol, 2 mM DTT, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2023 Feb 6
...Protein 10 Stimulators Studied by Small Angle X-ray Scattering International Journal of Molecular Sciences 24(17):13649 (2023)
...W, Fisher S, Lou J, Sele C, Ma S, Rasmussen A, Pinotsis N, Kozielski F
RgGuinier 1.7 nm
Dmax 5.6 nm
VolumePorod 19 nm3

SASDCB9 – ...protein Particle (NLP) assembled with tail-deuterated DMPC - 100% D2O SANS

Apolipoprotein A-I1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine experimental SAS data
Apolipoprotein A-I 1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine Kratky plot
Sample: ...protein A-I dimer, 50 kDa Mus musculus protein
1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine , 99 kDa
Buffer: PBS in D2O, pH: 7.4
Experiment: SANS data collected at NG7, NIST Center for High Resolution Neutron Scattering (CHRNS) on 2016 Apr 11
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 4.3 nm
Dmax 10.7 nm

SASDCC9 – ...protein Particle (NLP) from In Vitro Assembly - 42% D2O SANS

Apolipoprotein A-I1,2-dimyristoyl-sn-glycero-3-phosphocholine experimental SAS data
Apolipoprotein A-I 1,2-dimyristoyl-sn-glycero-3-phosphocholine Kratky plot
Sample: ...protein A-I dimer, 50 kDa Mus musculus protein
1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
Buffer: PBS in 42% D2O, pH: 7.4
Experiment: SANS data collected at NGB 30m SANS, NIST Center for High Resolution Neutron Scattering (CHRNS) on 2015 Dec 11
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 2.9 nm
Dmax 7.3 nm

SASDCD9 – ...protein Particle (NLP) from Cell-Free Expression - SAXS

1,2-dimyristoyl-sn-glycero-3-phosphocholineApolipoprotein A-I experimental SAS data
1,2-dimyristoyl-sn-glycero-3-phosphocholine Apolipoprotein A-I Kratky plot
Sample: 1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
...protein A-I dimer, 52 kDa Mus musculus protein
Buffer: PBS in D2O, pH: 7.4
Experiment: SAXS data collected at SAXSLab Bio-Ganesha, Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology (IBBR/NIST) on 2015 Nov 24
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 4.7 nm
Dmax 12.7 nm

SASDCE9 – ...protein Particle (NLP) with Telodendrimer - SAXS

1,2-dimyristoyl-sn-glycero-3-phosphocholineApolipoprotein A-I experimental SAS data
1,2-dimyristoyl-sn-glycero-3-phosphocholine Apolipoprotein A-I Kratky plot
Sample: 1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
...protein A-I dimer, 52 kDa Mus musculus protein
Buffer: PBS in D2O, pH: 7.4
Experiment: SAXS data collected at SAXSLab Bio-Ganesha, Institute for Bioscience and Biotechnology Research, National Institute of Standards and Technology (IBBR/NIST) on 2015 Nov 24
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 4.4 nm
Dmax 12.7 nm

SASDCF9 – ...protein Particle (NLP) from Cell-Free Expression - 100% D2O SANS

1,2-dimyristoyl-sn-glycero-3-phosphocholineApolipoprotein A-I experimental SAS data
1,2-dimyristoyl-sn-glycero-3-phosphocholine Apolipoprotein A-I Kratky plot
Sample: 1,2-dimyristoyl-sn-glycero-3-phosphocholine , 92 kDa
...protein A-I dimer, 52 kDa Mus musculus protein
Buffer: PBS in D2O, pH: 7.4
Experiment: SANS data collected at NG7, NIST Center for High Resolution Neutron Scattering (CHRNS) on 2015 Nov 25
...protein particles. Protein Sci 27(3):780-789 (2018)
...W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P
RgGuinier 3.5 nm
Dmax 12.5 nm

SASDLF9 – ...W protein (PNT3)

Protein W experimental SAS data
200-310 region of Hendra virus P/V/W protein (PNT3) Rg histogram
Sample: Protein W monomer, 15 kDa Hendra virus (isolate … protein
Buffer: 50 mM sodium phosphate, 5 mM EDTA, pH: 6.5
Experiment: SAXS data collected at ...WING, SOLEIL on 2021 Jun 12
...W Proteins Responsible for Phase Transition and Amyloid Formation Biomolecules 11(9):1324 (2021)
Salladini E, Gondelaud F, Nilsson J, Pesce G, Bignon C, Murrali M, Fabre R, Pierattelli R, Kajava A, Horvat B, Gerlier D, Mathieu C, Longhi S
RgGuinier 3.4 nm
Dmax 15.5 nm
VolumePorod 38 nm3